DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ppk23 and Asic2

DIOPT Version :9

Sequence 1:NP_001097011.1 Gene:ppk23 / 32731 FlyBaseID:FBgn0030844 Length:591 Species:Drosophila melanogaster
Sequence 2:NP_037024.2 Gene:Asic2 / 25364 RGDID:2017 Length:563 Species:Rattus norvegicus


Alignment Length:562 Identity:128/562 - (22%)
Similarity:213/562 - (37%) Gaps:159/562 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 LHGVRYIAESGRPIGEKF----MW---FCFTSIGAVTALVIIMS-----LWEKFQTNPTITGLDT 92
            |||:|::.......|..|    :|   || ||:|    |::..|     .|..|   |:.|.:..
  Rat    66 LHGLRHMCAGRTAAGGSFQRRALWVLAFC-TSLG----LLLSWSSNRLLYWLSF---PSHTRVHR 122

  Fly    93 DFHNQNVVFPTTVVC-------PEAA------FDH-------DKTYEKVYNTLANYDEAQAQMY- 136
            ::..| :.||...||       |..:      ..|       ::|...:.:.|...||.:.|.: 
  Rat   123 EWSRQ-LPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQWFR 186

  Fly   137 --TPFLRILTSLNFENVRDAKVLSQSIPQNLLDAHTIREWAFEGHIDCKNVFVSCKYRDEDIPCC 199
              ..|...|...:||.:      |.:....|            || ..:::.:|||||.|  .|.
  Rat   187 KLADFRLFLPPRHFEGI------SAAFMDRL------------GH-QLEDMLLSCKYRGE--LCG 230

  Fly   200 DH-FEPIYTEHGFCYAFNSRFKSTP-TEDVKTGAPHDL-----YETDKKWALFFIPNSTSRIFIF 257
            .| |..::|::|.||.|||.....| ...||.|..:.|     .:.|:     ::|     |:..
  Rat   231 PHNFSSVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDE-----YLP-----IWGE 285

  Fly   258 SNEEYFGSDFNAQI-DWSEPQLVE-----VRISKKNTYTTDDARQLSI----GQRKCIFSDEVKL 312
            :.|..|.:....|| ..|||..::     |....:....|.:.|...:    |:.:   |.|:.|
  Rat   286 TEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECR---SSEMGL 347

  Fly   313 NYFPDAYTFSSCMKQCRMNKAIKLCKC-------NPPFYKPIRELSCVINIFTNLIAYILLLYLT 370
            ::|| .|:.::|...|.....::.|.|       :.||..|.:...|.                 
  Rat   348 DFFP-VYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECA----------------- 394

  Fly   371 PKANVPMCSIKDFD-CLDEFKSNITNI-KDCLQCELSCSKTVFNIDKLIKMSDRPESLGVLV--- 430
             :..:.:.:.||.: ||.....|:|.. |:....::....:...::|....|::..|..:||   
  Rat   395 -EPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDI 458

  Fly   431 --EFLTWPIIRYKR--EVLFGWVDLLVSFGGIASLFLGFSLLSGVEIIYYFTLRACCMVYKNRQE 491
              |.|.:..|..|:  ||    ..||...||...||:|.|||:.:|:..|               
  Rat   459 FFEALNYETIEQKKAYEV----AALLGDIGGQMGLFIGASLLTILELFDY--------------- 504

  Fly   492 LYE-IEEKI-----RQEPPPKIDLKLS----LKSHNPRIGDT 523
            :|| |:||:     ::|.....|..:|    :.:|:..|..|
  Rat   505 IYELIKEKLLDLLGKEEEEGSHDENMSTCDTMPNHSETISHT 546

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ppk23NP_001097011.1 ASC 34..476 CDD:279230 116/503 (23%)
Asic2NP_037024.2 ENaC 64..557 CDD:273304 128/562 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D303969at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11690
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.020

Return to query results.
Submit another query.