Protein Alignment ppk23 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001097011.1
• Gene: ppk23 / 32731
• FlyBaseID: FBgn0030844
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 664
• Identity: 128/664 - (19%)
• Similarity: 209/664 - (31%)
• Gaps: 236/664 - (35%)

  Fly    29 YQTKE----FFQNSTLHG-VRYIAESGRPIGEKFMWFCFTSIGAVTAL----VIIMSL--WEKFQ 82
            |..||    :..|:..|| .|.|.|..:   :|.|||..|.:.|....    |.|.:.  ||
  Rat    20 YTYKELLVWYCNNTNTHGPKRIICEGPK---KKAMWFLLTLLFACLVCWQWGVFIQTYLSWE--- 78

  Fly    83 TNPTITGLDTDFHNQNVVFPTTVVCPEAAFDHDK--------------TYEKVYNTLANYDEAQA 133
               ....|...|...|  ||...||..:.|.:.|              ..:|:....:::....:
  Rat    79 ---VSVSLSMGFKTMN--FPAVTVCNSSPFQYSKVKHLLKDLYKLMEAVLDKILAPKSSHTNTTS 138

  Fly   134 QM------YTPFLRI---------------------------------------LTSLN-----F 148
            .:      :||.:.|                                       |.|.|     |
  Rat   139 TLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTF 203

  Fly   149 ENVRDA-------------KVLSQSIPQNLLDAHTIREWAFEGHIDCKNVFVSCKYRDEDIPCCD 200
            .|...|             .:.||.:||:|:..         |:.. ..:.::|.:..|  ||..
  Rat   204 RNFTSATQAVTEWYILQATNIFSQVLPQDLVGM---------GYAP-DRIILACLFGTE--PCSH 256

  Fly   201 -HFEPI-YTEHGFCYAFNSRFKSTPTEDVKTGAPH------DLYETDKKWALFFIPNSTS----- 252
             :|.|| |.::|.||.||.............|...      |:.:.|      ::|...|
  Rat   257 RNFTPIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQED------YVPFLASTAGAR 315

  Fly   253 ------RIFIFSNEEYFGSDFNAQIDWSEPQLVEVRISKKNTYT--TDDARQLSIGQRKCIFSDE 309
                  |.:.|..||  |....|..:.|...|::....|...|:  |.:...::|   :.::||
  Rat   316 LMLHEQRTYPFIREE--GIYAMAGTETSIGVLLDKLQGKGEPYSPCTMNGSDVAI---QNLYSD- 374

  Fly   310 VKLNYFPDAYTFSSCMKQCRMNKAIKLCKCNPPFYKPIRELSCVINIFTNLIAYILLLYLTP-KA 373
                 :...|:..:|:..|..:..|..|.|..                          ||.| .|
  Rat   375 -----YNTTYSIQACLHSCFQDHMIHNCSCGH--------------------------YLYPLPA 408

  Fly   374 NVPMCSIKDFD----CLDEFKSNITNIKDCL-QCELSCSKTVFNIDKLIKMSDRPES------LG 427
            ....|:.:||.    |....:.::...:.|| .|:.||:.|.:.:  .|.|:|.|..      |.
  Rat   409 GEKYCNNRDFPDWAYCYLSLQMSVVQRETCLSMCKESCNDTQYKM--TISMADWPSEASEDWILH 471

  Fly   428 VL---------VEFLTWPIIR---YKREVLFGWVD---------LLVSFGGIASLFLGFSLLSGV 471
            ||         :......|::   |.:|..:..::         ||.:.||....::|.|:|..:
  Rat   472 VLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLI 536

  Fly   472 EI---------IYYFTLRACCMVYKNRQELYEIEEKIRQEPPPKIDLKLSLKSHNPRIGDTPTSA 527
            |.         |....|.|.|...:.|:     .::....|||.:          ..:.:..|:.
  Rat   537 EFGEIIIDFIWITVIKLVASCKGLRRRR-----PQRPYTGPPPTV----------AELVEAHTNC 586

  Fly   528 VLKVKPAEESAGPN 541
            |.  :|...|..||
  Rat   587 VF--QPDTTSCRPN 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk23	NP_001097011.1	ASC	34..476	CDD:279230	112/588 (19%)
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	127/663 (19%)
		deg-1	29..538	CDD:273309	110/576 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820