Protein Alignment ppk23 and asic-2

DIOPT Version :10

• Sequence 1: NP_001097011.1
• Gene: ppk23 / 32731
• FlyBaseID: FBgn0030844
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 582
• Identity: 117/582 - (20%)
• Similarity: 193/582 - (33%)
• Gaps: 191/582 - (32%)

  Fly    32 KEFFQNSTLHGVRYIAESGRPIGEKFMWFCFTSIGAVTALVIIMSLWE------KFQTNPTITGL 90
            |:|...||:..|.::|.:...|...| |.      |:...|:.|..:|      ||.:.|.....
 Worm    11 KDFSNWSTVAVVPHVANANNKISRIF-WI------AIFLFVLGMFAYELYILIAKFFSYPATVNT 68

  Fly    91 DTDFHNQNVVFPTTVVCPEAAFDH-----DKTYEKVYNTLANYDEAQAQMYTPFLRILTSLNFEN 150
            :..|..|  :||...||....:.:     :..:..|...:..|.:|....::.....|.:.|.|.
 Worm    69 EILFEKQ--IFPVVTVCNMNPYKYSVVKSNSAFSSVNTLMTTYSDATVGTFSTDKWGLYADNDET 131

  Fly   151 -----------VRDAKVLSQS--IPQNLLDAHTIREWAFEGHIDCKNVFVSCKYRDEDIPCCD-- 200
                       |.:|.::|.:  :|.....|..|::.:|.|                 |||.:
 Worm   132 YDLDSRAADALVLEANLISDTAKVPALYTYADLIQDCSFAG-----------------IPCSESD 179

  Fly   201 ---HFEPIYTEHGFCYAFNS-----------------RFKSTPTEDVKTGAPHDLYETDKKWALF 245
               ..:|:|   |.||:||.                 :...|.|: .||....|...|.|.
 Worm   180 FTKFIDPVY---GACYSFNEDASLNYSVSREGIQFGLKLMLTVTQ-TKTNGNTDSLPTTKL---- 236

  Fly   246 FIPNSTSRIFIFSNEEYFGSDFN---AQIDWSEPQLVEV--RISKKNTYTTDDARQLSIGQRKCI 305
                :.:||.:.|.....|.|.|   |.:.:.....|.:  .:..|..|.|            |:
 Worm   237 ----AGARIGVNSRGSSPGLDSNGIDAGVGYESAVSVSLTQNVRAKKPYGT------------CV 285

  Fly   306 FSDEVKLNYFPD-AYTFSSCMKQCRMNKAIKLCKC-NPPFYKPIRELSCVINIFTNLIAYILLLY 368
            ..:....:|:.| .||..:|...|:....|..|:| ||.                      |.|.
 Worm   286 DREPDSSDYYKDFIYTLETCFNGCKQRDTIAKCQCANPR----------------------LALG 328

  Fly   369 LTPKANVPMCSIKDFDCLDEFKSNIT----NIKDCLQCEL------------------------- 404
            .|..|..|:.:  |.|||...|.|.|    ||...::|..
 Worm   329 STDTACQPIKA--DLDCLQTLKGNQTSSTPNIDLLVECNCNPPCDESTYTPTVSLAQFPSTSYYV 391

  Fly   405 ---------SCSKTVFNIDKLIKMSDRPE-------SLGVLVEFLTWPIIRYKREVLFGWVDLLV 453
                     |||.|   ..|....||..:       .:.|.:|.|::.:  |.....:...:::.
 Worm   392 ATSSTAGVGSCSST---NSKFSSKSDCQKWYNNNGMIIQVFLETLSYEL--YTETAGYTVSNVIN 451

  Fly   454 SFGGIASLFLGFSLLSGVEII-YYFTLRACCMV------------YKNRQELYEIEEKIRQE 502
            ..||.|.|:||.|::|.||:. ....:.|.|:.            .:|...:.::|: :::|
 Worm   452 DLGGQAGLWLGLSVISVVEMTGLMLVMGAFCVTGGAIKMAPDDDEIENDHRIKDVED-VKKE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk23	NP_001097011.1	ASC	34..476	CDD:459966	111/540 (21%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	111/540 (21%)