Protein Alignment CG43658 and syd

DIOPT Version :9

• Sequence 1: NP_001259643.1
• Gene: CG43658 / 32729
• FlyBaseID: FBgn0263706
• Length: 2263
• Species: Drosophila melanogaster
• Sequence 2: NP_524652.1
• Gene: syd / 43905
• FlyBaseID: FBgn0024187
• Length: 1227
• Species: Drosophila melanogaster
• Alignment Length: 1313
• Identity: 269/1313 - (20%)
• Similarity: 454/1313 - (34%)
• Gaps: 417/1313 - (31%)

  Fly   713 ERDRNLERDRDRERDKNDDLGEE---EVLTEEEQTSSSVSSL-----------SAGNQRNSQLRS 763
            ||:::..:..:::..:.:||.|:   |:.|..|...|.|..|           |...:|.:.|:.
  Fly   108 EREKSARKQSEQKLLEAEDLAEQENKELATRLESVESIVRMLELKHKNSLEHASRLEEREADLKK 172

  Fly   764 TFNKA--------KQHLSFDKWRTAATGSATGSASGPGSSATDSNNAASNMIMRRASACTMPSSG 820
            .:||.        |.|:.:.: ||.....:|.|.....|...|.:.|..|.:.|         |.
  Fly   173 EYNKLHERYTELFKNHVDYME-RTKMLMGSTHSQMSTASERMDVSRARLNPVAR---------SS 227

  Fly   821 GGGGAGVGSSQREEATTPGESPGGRLSRWFSIRRGSSHQYDVGGRDGRHSTASSFDTPDSGSGNS 885
            |....|..|.:.                  |:...:.....||.:           :.|||
  Fly   228 GPVSYGFASLEN------------------SVMLDTETICSVGSQ-----------SDDSG---- 259

  Fly   886 PKNGSNAVAGTGGAGSQGVALD-------AASPQKLANLGASKMMPGVPES-------------- 929
            |.:..|.:....|...:|.|.|       |.|||   :..:|.::|.||.:
  Fly   260 PPSLQNELDNLSGTLERGAATDALQQQHHATSPQ---SPDSSPVVPNVPTNVGRSTTKKEQRSDN 321

  Fly   930 ---------EDDEATANRFDVDLMMTPGSRANGTARTAHNRLIVPMLPPAPAGLSQQQLKRRHIV 985
                     :::|:..|.......:.||..|:    :|::...         |:.::       |
  Fly   322 NLYQELSFQDNEESEENEIVTGSWVHPGEYAS----SANDNYF---------GMGKE-------V 366

  Fly   986 AAIVHSENSYVATLQRLVNDYKKPLEECSPPVLNPVKIATLFHCLPDILHSHKLFRISLAECVRN 1050
            ..::...|..:|| :..:|..|..|         .||:
  Fly   367 ENLIMENNELLAT-KNALNIVKDDL---------IVKV--------------------------- 394

  Fly  1051 WDRDEKIGDCFVSAFGKPQLLEIYSGFINNFSAAMELAKME-EKRKSALADFFK-----VKQ--- 1106
               ||..|:           :||....:|    ||:.::.: .:|.|.|.|..|     |||
  Fly   395 ---DELTGE-----------VEIVREELN----AMQQSRTKLRQRISELEDELKKAKEQVKQQNT 441

  Fly  1107 ------ISAHDRLSF----FGLMVKPVQRFPQFILFLQDLLKYT-------PQGHHDRMSLQLAL 1154
                  :....|..|    ..:::....::.:.::.||:.::.|       ...:.||.|.|
  Fly   442 EQEENDVPLAQRKRFTRVEMAMVLMERNQYKERLMELQEAVRLTEILRASRTVDNLDRKSKQ--- 503

  Fly  1155 SQLELLAELLNESKREAEQYQ---AFKEMLGHISGTFNARSLSLSSVSVSDSAGGHRPRYLLRED 1216
            |..:..:.|...|.|..|:..   ....|..|..|...|.|....|   ..|.||.....|....
  Fly   504 SIWKYFSNLFTPSNRPTERVADGLGGGPMFRHTGGGSPAHSHGSPS---RGSGGGDNRLALTSGQ 565

  Fly  1217 NVTHMEFNQAGFIVKCKQRRLLLLNDKVICVSVAPKQSHDFGATEKLT----------------- 1264
            ...|..  .||           |.|     ..:.||...:.|::|:::
  Fly   566 PPVHPA--SAG-----------LAN-----ALIMPKDYAEEGSSERISARRREQYRQLRAHVQKE 612

  Fly  1265 ------FKWMFPVNDVEIVDN------------------STSATLSRILTAGLNRGGSLKSNGSS 1305
                  :.|..|:|......|                  ..|..:.....||:|..|....||.|
  Fly   613 DGRLHAYGWSLPINKASQEANPNRHSGGVPVPVYCNPLAEASPHMKVFCAAGVNLHGGFTKNGQS 677

  Fly  1306 --GANGSPYA-NSTLPGHGGGVSGFSGFGDPHSSPAAQLTNGADNLCSEMS--TLMYDYEVISRI 1365
              .|| |||| .|||.           ..:..|..|.|.....|...:.:|  ||..:.::.|.:
  Fly   678 LIPAN-SPYAPKSTLK-----------IAEITSPTADQSMEALDRQMARVSLETLEPETQLSSFV 730

  Fly  1366 QDLVSSLKGS-YKELNANTTRNVLNL-------------IQGSIQRKDEEMAWVDSCCLQLIGRH 1416
            ....|:...| ...::||.:..||:.             :||:::.        |...|:.....
  Fly   731 WICTSTHAASTVSVVDANQSATVLDAFPICASHLLCIASVQGAMES--------DYALLEQSEVV 787

  Fly  1417 KSGKEETFTFQTQTPAVKKEWITE---LRLAQLALDPNNSPAWERGGSHPQPAHHHPHHHPLQHP 1478
            |:|:      ..|.|....|.:.:   :|:...:.|..||
  Fly   788 KAGE------MLQRPGEGTELLGKVEFVRVKPKSDDEQNS------------------------- 821

  Fly  1479 HAGAGDPRQTQEQLQLQEAVQQKQSRKMPLFVKAMPVYKSQHQTEVR---CGCYYSIANDTKQSG 1540
                 :.:|.||:.:.:||. :|.:.::|. |.|.....:....::|   .|....::.|..|:.
  Fly   822 -----NEKQQQEEEEAKEAT-EKSNEQLPA-VSAEEPLGNVEAIKIRQPLPGAPQRLSTDGNQTN 879

  Fly  1541 NARRRHKQLNYLWMCSSDGTSSHITVLAQHPQQAGNLREAGAFDLFETQVSALEFVKGLD---QL 1602
            |               ::.:||           :.||       ||.|        |.|:   :.
  Fly   880 N---------------NNNSSS-----------SSNL-------LFAT--------KSLNPILET 903

  Fly  1603 KSRDEPA-SLLGDLVWLGTDSRKILIYSARNPEQEEQLGSYSVPGAVQRILYHFDAVYVALSGAT 1666
            |.||||| |.:|..:|||.....:.::|:.. ...|.|....:|.||..|::....|.|||:.|.
  Fly   904 KDRDEPAMSSVGPTMWLGAQDGWLYVHSSVG-RWHECLHRVLLPDAVLAIVHVEARVVVALANAQ 967

  Fly  1667 VLIFRRGNDGVWQLRDPQTIRLGDTDLVVPSLLPINMCIYASCGNRVYVMNALNGEIQRSFEVQH 1731
            :.:|||..||.|.|.....:.|||.:..:..|......|:|:..|::::::.::..|..|.:...
  Fly   968 LAVFRRQTDGQWDLNSYHLVTLGDRNHSIRCLCVAGERIWAAHRNKIFIVDPVSLNIVHSLDAHP 1032

  Fly  1732 GATQQVNLMAHSGIGLWISLKNSTMLCLYHTETFKHLQDINIASSVLRHDGKKEQPLNNSSVYVT 1796
            ....||..||.:|.|:|:|::..:.|.||:|.||:|.||::|...|.:..|..:  |..|.|.:|
  Fly  1033 RKESQVRQMAATGAGVWVSIRLDSTLRLYNTHTFEHKQDVDIEPYVSKMLGTGK--LGFSFVRIT 1095

  Fly  1797 ALMACKGLLWVGTNVGIAVTIPL----PRLEGVPIISGGINMSC--------HAHFGPITFLLPL 1849
            |||.....||:||:.|:.:::||    |:....|  .|.:.:.|        |.|...:.|.:.:
  Fly  1096 ALMVSCNRLWIGTSNGVIISVPLAEVQPKSSSDP--HGQMPLCCMANAQLSFHGHRDAVKFFVSV 1158

  Fly  1850 IPKVYPAYKPPTV 1862
                 |..:.|.:
  Fly  1159 -----PMLQQPNL 1166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43658	NP_001259643.1	RhoGEF	984..1153	CDD:279015	34/194 (18%)
syd	NP_524652.1	Jnk-SapK_ap_N	43..196	CDD:286787	19/88 (22%)
		JIP_LZII	362..430	CDD:293080	21/129 (16%)
		Vps53_N	374..>524	CDD:282020	38/207 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910