Protein Alignment CG5613 and Engase

DIOPT Version :9

• Sequence 1: NP_573215.1
• Gene: CG5613 / 32726
• FlyBaseID: FBgn0030839
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_006247865.1
• Gene: Engase / 303702
• RGDID: 1310868
• Length: 733
• Species: Rattus norvegicus
• Alignment Length: 690
• Identity: 214/690 - (31%)
• Similarity: 304/690 - (44%)
• Gaps: 154/690 - (22%)

  Fly    30 GITTEEEEEVVPVKKKRTEEGGGELKEVACEKETVQRE-----------KCQDKNTCRCSQLEAE 83
            |.|..|::.....:::|..:|....|:.  |:|.|.|:           :..||:|.|
  Rat    16 GSTAPEKQAQDQPERRRRRQGRRINKDQ--EEEAVFRDVVNFAPDPLPARYYDKDTTR------- 71

  Fly    84 PIKDNRQLLEFRVRSRNIDWREYVLPLDTSVRTTPVYLDRQADFVG--------STRRQVTEDNR 140
            ||.                  .|:..|:..:..||:..|      |        ..|:......|
  Rat    72 PIS------------------FYLSTLEELLAWTPLMED------GFNVALEPLECRQPPLSSPR 112

  Fly   141 RELLVCHDMMGNYLEDRHFHSSQKYDDYRFVHWSAVDYFCYFSHDYVTIPPCGWLNAAHRHGVPV 205
            ...|:||||||.|||||....|:..:.|.|.||..:|.|.||||..|||||..|.||||||||.|
  Rat   113 PRTLLCHDMMGGYLEDRFIQGSEVQNPYSFYHWQYIDIFVYFSHHTVTIPPVCWTNAAHRHGVCV 177

  Fly   206 VGTFIVE--ATARLDE-FLASEE-SVESTVEALTRLCEHFGFEGWLVNVEVTVPLAKMPRLYRFV 266
            :||||.|  ...:|.| |||.:| |.::..:.|.::.:.|.|:|||:|:|.::..|.:.....|:
  Rat   178 LGTFITEWQEGGKLCEAFLAGDERSFQAVADRLVQIAQFFRFDGWLINIENSLSPAAVRNTPLFL 242

  Fly   267 RQLTAATESRVPHGRVFWYDSVTDDGQLRWQNELNSRNAKFFRHSHGTLINYAWDEGHLERSAQQ 331
            :.||.....:||.|.|.|||||...|||:||:|||.:|..||....|...||.|.|.||:|...|
  Rat   243 QYLTRQLHQQVPGGLVLWYDSVVQSGQLKWQDELNEQNRVFFDSCDGFFTNYNWREDHLKRMVAQ 307

  Fly   332 VRREQSPRHRVFMGLDVFGRSR--KGGFHSWETMELIAKNGFSAGIFAPGWTFETLNRFGYNIKN 394
            .....:.   |::|:|||.||.  .|.|.:.:::|||.|:||||.:|||||.:|.|.      ||
  Rat   308 AGERLAD---VYVGIDVFARSNVVGGRFDTDKSLELIRKHGFSAALFAPGWVYECLE------KN 363

  Fly   395 PRGDDQVNASFLARNEAWWSRIWPTLATHPYTSLPFFTDFCVGSGRAKFERGWRILGED---SPF 456
                     .|....:.:|..:...|.||...||||.|.||:|.|..:.     ..|::   .|:
  Rat   364 ---------DFFQNQDKFWRLLERFLPTHSICSLPFVTSFCLGLGTRRV-----CYGKEQAVGPW 414

  Fly   457 FNLSRQSLQPSVPLGRNAMHHFD-----------EAYSGGCSLLVTNY------ERAFRLFVTDF 504
            ::.|.|..||.  .|.:.:...:           :|:.||.|||:...      ..|.|||....
  Rat   415 YHPSAQETQPL--FGEHKLAGGNRGWVKTHCCLVDAWHGGSSLLLRGLIPPEVDSVAVRLFSMHV 477

  Fly   505 ELDRGVLLLRYVFKIDGDAVGTMFDLLVRVTPLRRNDQDLHLFCGD----YEGSIV---APQRCY 562
            .:...| .|..|:|.:|..     |:.|.          |.|..||    :.|.::   |.....
  Rat   478 PVPPKV-FLSMVYKFEGST-----DVQVA----------LELTTGDASSCHVGGVLVLNAETGTR 526

  Fly   563 LSPHESDLPSGLFRLHHDSSS----LAAGWQMRDYLVKFDGPVRVQDIGVKYQRP----SESSTD 619
            .||....:|.  .||...:||    |:.||..|.|.|...|.: :||:.|.:.||    .|.|..
  Rat   527 YSPRPLRVPP--TRLARWASSCGQQLSGGWIQRCYEVNLRGCL-LQDLLVSFSRPPGSREEESFI 588

  Fly   620 AKLGFVY-------------VDGLTLEDLKDTWTDIPVYS 646
            .:||.:.             |..:|:..|:  |  :|:.|
  Rat   589 CRLGEIQVVDANSLLAPLPRVQNVTISQLR--W--LPLIS 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5613	NP_573215.1	GH85_ENGase	144..476	CDD:119364	138/340 (41%)
Engase	XP_006247865.1	GH85_ENGase	116..426	CDD:119364	137/334 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353901
Domainoid	1	1.000	223	1.000	Domainoid score	I2489
eggNOG	1	0.900	-	-		E1_COG4724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3195
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D479155at33208
OrthoFinder	1	1.000	-	-		FOG0005197
OrthoInspector	1	1.000	-	-		oto95824
orthoMCL	1	0.900	-	-		OOG6_104188
Panther	1	1.100	-	-	LDO	PTHR13246
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3708
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.760