DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8611 and AT3G16840

DIOPT Version :9

Sequence 1:	NP_788922.1	Gene:	CG8611 / 32725	FlyBaseID:	FBgn0027602	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_001326753.1	Gene:	AT3G16840 / 820937	AraportID:	AT3G16840	Length:	827	Species:	Arabidopsis thaliana

Alignment Length:	865	Identity:	198/865 - (22%)
Similarity:	351/865 - (40%)	Gaps:	204/865 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 LPTPGDLFRAQLEEERRQKRREEGGGDQEASADEEDAKNNSGGGSPRVKPSSAVKESKKSSDIED 244
            |||        :|.|..::::         |.:::|..|.:            |.|..:..:.|:
plant    79 LPT--------IESEITERKQ---------SPEDDDDTNET------------VDEMIEGEEAEE 114

  Fly   245 SGESGEESATSDEEPDESSAQSPGQEKEPKQTAKKPPKAEETSSTNRFRTKKIGLFDQSDVEALK 309
            .||..::....|:|......:...:..:.|:..||..|.::.:...:.:.....:....|....:
plant   115 DGEGRDDEDDEDDEETRKKKEKKAKRNKEKKKEKKKKKQKKINEAAKNQDASAAVSCDGDDTVEE 179

  Fly   310 QLGQRAVKPVKETIFTGSKISTLGLHPHAVKNLEDLLSIRELTSVQQKTI-PEVLQGKDVLVRSQ 373
            |:.:..:.|      ..|..|::.|||..:|::. .|..:|.|.:|:... ....|||||:..::
plant   180 QVEEEEIPP------EFSAWSSMRLHPLLMKSIY-RLDFKEPTKIQKACFNVAAYQGKDVIGAAE 237

  Fly   374 TGSGKTLAYALPLVELLQKQQPRIQR-------------KDGVL-ALVIVPTRELVMQTYELIQK 424
            ||||||||:.||:::.|..::.::.:             .||.| ||:|.|||||.:|..|.::.
plant   238 TGSGKTLAFGLPILQRLLDEREKVGKLYALKGEEAQKYAADGYLRALIITPTRELALQVTEHLEN 302

  Fly   425 LVKPYT-WIVPGSLLGGESRKSEKARLRKGINILIGTPGRLVD-------HLLHTASFKLTKLQF 481
            ..|..: .:||  ::||...:.::.||::...|::.|||||.:       ||:     :|..|.|
plant   303 AAKNLSVKVVP--IVGGMFSEKQERRLKEKPEIVVATPGRLWELMSAGEKHLV-----ELHSLSF 360

  Fly   482 LILDEADRLLELGYERDVKQLVEAI---DK------QRAECEDKEL--PQLQR--MLLSATLTSQ 533
            .:||||||::|.|:.|:::.:::.:   ||      |..:..|..|  |:.:|  .:.|||:.
plant   361 FVLDEADRMVERGHFRELQSILDLLPVTDKPNEGKTQTVKSNDTVLNVPKKKRQTFVFSATIA-- 423

  Fly   534 VQQLAGLTLKNPLYIDNSDEAASAALKSKDGYQKE--TIEALLE---VDDGLGEYQEDVTGVLSI 593
                        |..|...:....:.|||.....|  :||.|.|   :.|.:.......|.:|:
plant   424 ------------LSSDFRKKLKRGSSKSKQSSSGEVNSIEVLSERAGMRDNVAIIDLTTTSILA- 475

  Fly   594 PENLQLSYVVVPPKLRLVALSSLLAKEVDASPKQFKAIVFMSTTEMVNFHHDMLNEALTRRVLDE 658
             ..::.|::....|.:...|..:|:..     .|.:.|||  .|.:.:..|
plant   476 -PKIEESFIKCEEKEKDAYLYYILSVH-----GQGRTIVF--CTSVTDLRH-------------- 518

  Fly   659 EDEQEKGDSDDDGDIPLLQGLRFFKLHGSMTQTERQGVFRGFRDCASCVLLATDVVGRGIDVPDI 723
                      ..|.:.:| ||....|...|.|..|......||...:.:|:|||:|.||||:.::
plant   519 ----------ISGLLKIL-GLDVCTLFSEMKQRARLKSIDRFRASENGILIATDLVARGIDIKNV 572

  Fly   724 KLVVQYTPPQTTADFVHRVGRTARAGRKGRAVLFLTPSEAQ----FVRHLEKKRIRIQQGDMYAY 784
            :.::.|..|.:...:|||.||||||...|.::..:.|:|..    ..:....:.::|...| .:|
plant   573 RTIIHYKLPHSAEVYVHRCGRTARAFADGCSIALIEPNETSKFYTLCKSFSMESVKIFPLD-NSY 636

  Fly   785 LQTLLPKDDEARTVQEAASNLQHKFQTLLEDDRELHDKSCKAFVSWMKFYSTF--------PKEL 841
            :..:..:...||.:.|    ::.|      ..||..|:      :|:|.::..        ..|.
plant   637 MPAVRKRLYLARQIYE----IERK------GSRENADR------TWLKKHAESMELELDDEESEE 685

  Fly   842 KPIFNVRIAHMGHFAKSFALKE----------APSKFAAKHAAPKAAPPTNRLTYTERDPEKIQA 896
            :.:.||| ......|:...|||          .|.||:.::.|........:..:.|...:| ||
plant   686 ERVDNVR-QRKATSARLNKLKEELSTLLSHPMQPKKFSGRYFAGVGVSTLMQNQFVELKKQK-QA 748

  Fly   897 QKR----AKRRFTTTVSGE-VRQLQ-------------------QRDVGAQKPGAPPPKGGFIGG 937
            |.:    .|||....::.. :..||                   :||:.:.|......|
plant   749 QMQIGGDIKRRKLVVINQNCIEPLQALRAGGNEMLKMKGQSAEKRRDIASLKKKRKEEK------ 807

  Fly   938 GVGRSSFMKSLGKSRALNMS 957
             :||....::..|.|.|..|
plant   808 -IGRRDQRRNQKKQRKLMAS 826

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8611	NP_788922.1	DUF2413	203..>285	CDD:287302	14/81 (17%)
		P-loop_NTPase	332..548	CDD:304359	75/251 (30%)
		DEXDc	348..554	CDD:214692	71/241 (29%)
		HELICc	601..757	CDD:238034	40/155 (26%)
		DUF4217	805..866	CDD:290667	14/78 (18%)
AT3G16840	NP_001326753.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920