DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8611 and AT2G40700

DIOPT Version :9

Sequence 1:	NP_788922.1	Gene:	CG8611 / 32725	FlyBaseID:	FBgn0027602	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_181602.2	Gene:	AT2G40700 / 818665	AraportID:	AT2G40700	Length:	610	Species:	Arabidopsis thaliana

Alignment Length:	619	Identity:	226/619 - (36%)
Similarity:	343/619 - (55%)	Gaps:	44/619 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   302 QSDVEALKQLGQRAVKPVKETIFTGSKISTLGLHPHAVKNLEDLLSIRELTSVQQKTIPEVLQGK 366
            |......||..:.|.| .|..:|.....|:|||.......|::.:.....|.||.:.||.:|.|:
plant     6 QQSARETKQEAKDASK-AKSGLFASCSFSSLGLDTKLSDQLKERMGFEAPTLVQAQAIPVILSGR 69

  Fly   367 DVLVRSQTGSGKTLAYALPLVELLQKQQPRIQRKDGVLALVIVPTRELVMQTYELIQKLVKPYTW 431
            ||||.:.||:|||:||..||:..||...|::.|..|..||||||||||.:|.||.::||:..:.|
plant    70 DVLVNAPTGTGKTIAYLAPLIHHLQGHSPKVDRSHGTFALVIVPTRELCLQVYETLEKLLHRFHW 134

  Fly   432 IVPGSLLGGESRKSEKARLRKGINILIGTPGRLVDHLLHTASFKLTKLQFLILDEADRLLELGYE 496
            ||||.::|||.:..|||||||||:|||.|||||:|||.:||||....|:::|.||||.:|||||.
plant   135 IVPGYVMGGEKKAKEKARLRKGISILIATPGRLLDHLKNTASFVHKNLRWVIFDEADSILELGYG 199

  Fly   497 RDVKQLVEAIDKQRAEC--EDKELP---QLQRMLLSATLTSQVQQLAGLTLKNPLYI--DNSDEA 554
            ::::|:::.:...:.|.  ||..:|   |.|.:||||||..:|..||.|:|.:|:.|  ||:...
plant   200 KEIEQIIKLLGSGQNEQGEEDDIVPKGIQKQNLLLSATLNDKVNDLAKLSLDDPVMIGLDNTKLQ 264

  Fly   555 ASAALKSKDGYQKETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPKLRLVALSSLLAK 619
            .:.:::|......:..:.::.|:.......||    ..||..|...|:.||...|||||.|:|..
plant   265 QNLSIESPAAPDSDAEDMVIHVNKSANPLSED----YGIPSQLVQRYLRVPCGARLVALLSVLKN 325

  Fly   620 EVDASPKQFKAIVFMSTTEMVNFHHDMLNEALTRRVLDEEDEQEKGDSDDDGDIPLLQGLRFFKL 684
            ..:....| |.:||.||.:.|:||:.:|:|.         ......:::::|...|....:.|:|
plant   326 LFEREASQ-KVVVFFSTRDAVDFHYSLLSEF---------QWPPNSETEEEGTKELFLKCKTFRL 380

  Fly   685 HGSMTQTERQGVFRGFRDCASCVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHRVGRTARAG 749
            ||||.|.:|:..|..|:.....|||:|||..||:|.|.::.::||..|....::|||||||||.|
plant   381 HGSMEQEDRRSAFGTFKTEKQAVLLSTDVAARGLDFPKVRCIIQYDCPGEATEYVHRVGRTARIG 445

  Fly   750 RKGRAVLFLTPSEAQFVRHLEKKRIRIQQGDMYAYLQTL--------LPKDDEARTVQEA--ASN 804
            .||.|:|||.|.|..:::.|:|....:.:   |..::.|        :|:..:..:::..  ..:
plant   446 EKGEALLFLQPIEIDYLKELKKHGASLTE---YPLMKVLDKFPIPGNMPRIKKVLSLESHPWVIS 507

  Fly   805 LQHKFQTLLEDDRELHDKSCKAFVSWMKFYSTFPKELKPIFNVRIAHMGHFAKSFALKEAPSKFA 869
            ||...::|...:.::...:..|||||::.|:....|||.||.|:..|:||.||||||:|.||...
plant   508 LQRALESLTYAEPKMKSLAKNAFVSWVRGYAAHKGELKSIFVVKKLHLGHVAKSFALREQPSLVG 572

  Fly   870 AKHAAPKAAPPTNRLTYTERDPEKIQAQKRAKRR 903
            ..|         ::.|...:..|:.:.|:..||:
plant   573 KSH---------HKETMKRKRDERQKGQQGKKRK 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8611	NP_788922.1	DUF2413	203..>285	CDD:287302
		P-loop_NTPase	332..548	CDD:304359	106/220 (48%)
		DEXDc	348..554	CDD:214692	105/212 (50%)
		HELICc	601..757	CDD:238034	59/155 (38%)
		DUF4217	805..866	CDD:290667	25/60 (42%)
AT2G40700	NP_181602.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	188	1.000	Domainoid score	I966
eggNOG	1	0.900	-	-		E2759_KOG0348
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6389
Inparanoid	1	1.050	370	1.000	Inparanoid score	I568
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	1	1.000	-	-		FOG0003502
OrthoInspector	1	1.000	-	-		oto4151
orthoMCL	1	0.900	-	-		OOG6_102676
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2393
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.830