Protein Alignment CG8611 and DDX31

DIOPT Version :10

• Sequence 1: NP_788922.1
• Gene: CG8611 / 32725
• FlyBaseID: FBgn0027602
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001309270.1
• Gene: DDX31 / 64794
• HGNCID: 16715
• Length: 755
• Species: Homo sapiens
• Alignment Length: 808
• Identity: 273/808 - (33%)
• Similarity: 440/808 - (54%)
• Gaps: 114/808 - (14%)

  Fly   192 EEERRQKRREEGGGDQEASADEEDAKNNSGGGSPRVKPSSAVKESKKSSDIEDSGESGEESATSD 256
            ::.:..||:      .:||::...||..:         .::...:||:| ::::..:.:.:|...
Human    34 KQAKATKRK------YQASSEAPPAKRRN---------ETSFLPAKKTS-VKETQRTFKGNAQKM 82

  Fly   257 EEPDESSAQSPGQEKEPKQTAKKPPKAEETSSTNRFRTKKIGLFDQSDVEALKQLGQRAVKPVKE 321
            ..|.:.|..:..:.:|.:|..|       |||          ||..:  ..:.:|.:..||.|:|
Human    83 FSPKKHSVSTSDRNQEERQCIK-------TSS----------LFKNN--PDIPELHRPVVKQVQE 128

  Fly   322 TIFTGSKISTLGLHPHAVKNLEDLLSIRELTSVQQKTIPEVLQGKDVLVRSQTGSGKTLAYALPL 386
            .:||.:....||||||.:..:..:|.:..:||||:::||.:|:|:|.||||||||||||||.:|:
Human   129 KVFTSAAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPV 193

  Fly   387 VELLQKQQPRIQRKDGVLALVIVPTRELVMQTYELIQKLVKPYTWIVPGSLLGGESRKSEKARLR 451
            |:.||..:.:|||.||..|||:||||||.:|:::.:|||:||:||||||.|:|||.|||||||||
Human   194 VQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLR 258

  Fly   452 KGINILIGTPGRLVDHLLHTASFKLTKLQFLILDEADRLLELGYERDVKQLVEAIDKQRAECEDK 516
            |||||||.||||||||:..|.:...::|::|:.|||||:|:||:|:|:..::.|::   |||:.:
Human   259 KGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVN---AECQKR 320

  Fly   517 ELPQLQRMLLSATLTSQVQQLAGLTLKNPLYIDNSDEAASAALKSKDGYQKETIEALLEV----- 576
                 |.:|||||||..|.:||.::|.:|:.|...|::.. .|..||       :|:.||
Human   321 -----QNVLLSATLTEGVTRLADISLHDPVSISVLDKSHD-QLNPKD-------KAVQEVCPPPA 372

  Fly   577 DDGLGEYQEDVTGVLSIPENLQLSYVVVPPKLRLVALSSLLAKEVDASPKQFKAIVFMSTTEMVN 641
            .|.|..:        :|||:|:....|||.|||||.|::.:.::......| |.:||.|:.|:|.
Human   373 GDKLDSF--------AIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQ-KMVVFFSSCELVE 428

  Fly   642 FHHDMLNEALTRRVLDEEDEQEKGDSDDDGDIP-LLQGLRFFKLHGSMTQTERQGVFRGFRDCAS 705
            ||:.:..:.|.          ....:...|.:| ....|:|.:|||.|.|.||..||:.|.....
Human   429 FHYSLFLQTLL----------SSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRR 483

  Fly   706 CVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHRVGRTARAGRKGRAVLFLTPSEAQFVRHLE 770
            .|||.|||..||:|:|.:..:|||..|.:.|:::||:|||||.|..|.::|.|.||||::|..|.
Human   484 GVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLA 548

  Fly   771 KKRIRIQQGDMYAYLQTLLPKDD---------------EARTVQEAASNLQHKFQTLLEDDRELH 820
            ..:|.:.:..|...| .:|.:||               ..:.::|.|:.||..|:..:.......
Human   549 SHKINVSEIKMEDIL-CVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRV 612

  Fly   821 DKSCKAFVSWMKFYSTFPKELKPIFNVRIAHMGHFAKSFALKEAPSKFAA----KHAAPKAAPPT 881
            ..:.||..|:::.|:|:|:|||.||:||..|:||.||||.|::||...:|    |..|....|..
Human   613 SWAKKALQSFIQAYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPRNLSALTRKKRKAHVKRPDL 677

  Fly   882 NRLTYTERDPEKIQAQKRAKRRFTTTVSGEVRQLQQRDVGAQKPGAPPPKGGFIGGGVGRSSFMK 946
            ::.|.::....:|     .:..:::.:..::.::::::.    ||.|       ||...:.|...
Human   678 HKKTQSKHSLAEI-----LRSEYSSGMEADIAKVKKQNA----PGEP-------GGRPLQHSLQP 726

  Fly   947 S--LGKSRALNMSEFDSGLPPEGAAKRR 972
            :  .|:.:.|...:...|:..:....::
Human   727 TPCFGRGKTLKWRKTQKGVQRDSKTSQK 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8611	NP_788922.1	PTZ00108	<6..263	CDD:240271	11/70 (16%)
		PRK11776	330..>770	CDD:236977	196/445 (44%)
		DEADc_DDX31	339..549	CDD:350707	112/209 (54%)
		DUF4217	806..866	CDD:464056	24/59 (41%)
DDX31	NP_001309270.1	SrmB	136..558	CDD:440279	198/456 (43%)
		DEADc_DDX31	145..348	CDD:350707	112/210 (53%)
		DUF4217	598..658	CDD:464056	24/59 (41%)