DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8611 and ddx1

DIOPT Version :9

Sequence 1:	NP_788922.1	Gene:	CG8611 / 32725	FlyBaseID:	FBgn0027602	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_001184253.1	Gene:	ddx1 / 556790	ZFINID:	ZDB-GENE-041001-215	Length:	740	Species:	Danio rerio

Alignment Length:	439	Identity:	115/439 - (26%)
Similarity:	180/439 - (41%)	Gaps:	110/439 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 VLVRSQTGSGKTLAYALPLVELLQKQQPRIQRKDGVLALVIVPTRELVMQTYELIQKLVKPYTWI 432
            |:..|||||.|.....      .....||        ||:|.|::||..||...:.:..|    .
Zfish   266 VVKSSQTGSAKVTQVK------SSSNAPR--------ALIIEPSKELAEQTLNNVNQFKK----Y 312

  Fly   433 VPGS------LLGGESRKSEKARLRKGINILIGTPGRLVDHLLHTASFKLTKLQFLILDEADRLL 491
            |...      ::||.:.|.:...|..|::|::|||||| |.|:.|....|::::||:|||.|.||
Zfish   313 VDNPKLRELLIIGGVAAKEQLNVLESGVDIVVGTPGRL-DDLISTGKLDLSQVRFLVLDECDGLL 376

  Fly   492 ELGYERDVKQLVEAIDKQRAECEDKELPQLQRMLLSATLTS-QVQQLAGLTLKNPLYIDNSDEAA 555
            ..|....:.::...|.:..::.:     :||.::.||||.| .|::|:...:..|.::|
Zfish   377 SAGNTDFIMRIYNQIPQVTSDGK-----RLQVIVCSATLHSFDVKKLSEKIMHFPTWVD------ 430

  Fly   556 SAALKSKDGYQKETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPK-----LRL----V 611
               ||.:|                            |:||.:....|.|.||     .||    :
Zfish   431 ---LKGED----------------------------SVPETVHHVVVTVNPKNDKLWERLGKNHI 464

  Fly   612 ALSSLLAKEVDASPKQFKAIVFMSTTEMVNFHHDMLNEALTRRVLDEEDEQE-------KGDSDD 669
            ....:.||: |..|.       .::.||.:....:|....|.|.:.|....:       |.|.|:
Zfish   465 RTDEVHAKD-DTRPG-------ANSPEMWSEAIKILKGEYTVRAIKEHKMDQAIIFCRTKIDCDN 521

  Fly   670 -------DGDIPLLQGLRF--FKLHGSMTQTERQGVFRGFRDCASCVLLATDVVGRGIDVPDIKL 725
                   .|..|..:|.:|  ..|||.....||:.....|:......|:.|||..|||||..:..
Zfish   522 MEQYFIKQGGGPDKKGHQFSCVCLHGDRKPNERKYNLERFKKQEVKFLICTDVAARGIDVRGVPY 586

  Fly   726 VVQYTPPQTTADFVHRVGRTARAGRKGRAVLFLTPSEAQFVRHLEKKRI 774
            |:..|.|....::|||:||..||.|.|.|:..:.         :||:::
Zfish   587 VINVTLPDEKENYVHRIGRVGRADRMGLAISLVA---------MEKEKV 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8611	NP_788922.1	DUF2413	203..>285	CDD:287302
		P-loop_NTPase	332..548	CDD:304359	55/186 (30%)
		DEXDc	348..554	CDD:214692	56/192 (29%)
		HELICc	601..757	CDD:238034	51/180 (28%)
		DUF4217	805..866	CDD:290667
ddx1	NP_001184253.1	SrmB	1..>62	CDD:223587
		P-loop_NTPase	4..>70	CDD:304359
		SPRY_DDX1	93..245	CDD:293933
		DEXDc	238..439	CDD:214692	60/233 (26%)
		P-loop_NTPase	266..426	CDD:304359	54/183 (30%)
		Helicase_C	493..609	CDD:278689	33/115 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010