Protein Alignment CG8611 and pit

DIOPT Version :9

• Sequence 1: NP_788922.1
• Gene: CG8611 / 32725
• FlyBaseID: FBgn0027602
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Alignment Length: 862
• Identity: 229/862 - (26%)
• Similarity: 372/862 - (43%)
• Gaps: 246/862 - (28%)

  Fly   139 KITRAERLGKKQRQGKPLTKLSEEQITRALKSNKKPKNPNQL-----------PTPGDLFRAQLE 192
            ||.:.|:: ||:...|...|.:::|.......||..|.|.:|           ....|...|.|.
  Fly    11 KIVKREKM-KKELSQKKGNKNAQKQEPPKQNGNKPSKKPEKLSKKHVAKDEDDDLEEDFQEAPLP 74

  Fly   193 EERRQKRR------EEGGGDQEASADEEDAKNNSGGGSPRVKPSSAVKESKKSSDIEDSGESGEE 251
            ::::||:.      :....|.|:..||::                  .|:.:.||:::..|..||
  Fly    75 KKKQQKQPPKKQQIQVANSDSESDDDEQE------------------DEADEDSDLDEVAEVDEE 121

  Fly   252 SATSDEEPDESSAQSPGQEKEPKQTAK-----------KPPKAEETSSTNRFRTKKIGLFDQSDV 305
            ...|..|.|:.......:|..|.:..|           ||.|.:|..:..    ..:...|..|.
  Fly   122 DVDSGSEDDDQQEDEDEEEPVPAKKTKLLPNKSKAQNGKPAKDDEPFTVE----SSLAALDYRDS 182

  Fly   306 E-----ALK-QLGQRAVKPVKETIFTGSKISTLGLHPHAVKNLEDLLSIRELTSVQQKTIPEVLQ 364
            :     :|| .:.:..::.:||..||                        |:|.:|.|::..:|:
  Fly   183 DDRSFASLKGAVSEATLRAIKEMGFT------------------------EMTEIQSKSLTPLLK 223

  Fly   365 GKDVLVRSQTGSGKTLAYALPLVELLQKQQPRIQRKDGVLALVIVPTRELVMQTYELIQKLV--K 427
            |:|::..:|||||||||:.:|.|||:.|.  |...::|...::|.|||||.|||:.::::|:  .
  Fly   224 GRDLVGAAQTGSGKTLAFLIPAVELINKL--RFMPRNGTGVIIISPTRELSMQTFGVLKELMAHH 286

  Fly   428 PYTWIVPGSLLGGESRKSEKARLRKGINILIGTPGRLVDHLLHTASFKLTKLQFLILDEADRLLE 492
            .:|:   |.::||.:|:.|..:|.||||||:.|||||:|||.::..|....||.||:||.||:||
  Fly   287 HHTY---GLVMGGSNRQVESEKLGKGINILVATPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILE 348

  Fly   493 LGYERDVKQLVEAIDKQRAECEDKELPQLQRMLLSATLTSQVQQLAGLTLKN-PLYI---DNSDE 553
            :|:|.::||::..:.|:|           |.||.|||.|::::.|:.|.||: |:|:   ||.|.
  Fly   349 IGFEEELKQIINLLPKRR-----------QTMLFSATQTARIEALSKLALKSEPIYVGVHDNQDT 402

  Fly   554 AASAALKSKDGYQKETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPKLRLVALSSLLA 618
            |      :.||                                |:..|:|.|.:.||:.|.:.|.
  Fly   403 A------TVDG--------------------------------LEQGYIVCPSEKRLLVLFTFLK 429

  Fly   619 KEVDASPKQFKAIVFMSTTEMVNFHHDMLNEALTRRVLDEEDEQEKGDSDDDGDIPLLQGLRFFK 683
            |.     ::.|.:||.|:...|.:||::.|..                     |:|:.      .
  Fly   430 KN-----RKKKVMVFFSSCMSVKYHHELFNYI---------------------DLPVT------S 462

  Fly   684 LHGSMTQTERQGVFRGFRDCASCVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHRVGRTAR- 747
            :||...||:|...|..|.:..|.:||.|||..||:|:|.:..:|||.||....:::||||||||
  Fly   463 IHGKQKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARG 527

  Fly   748 AGRKGRAVLFLTPSEAQFVRHLEKKRIRIQQGDMYAYLQTLLPKDDEARTVQEAASNLQHKFQTL 812
            :|..|.|:|.:.|.|..|:|:|:..::.:                :|.....:..:::|.:.:.|
  Fly   528 SGTSGHALLLMRPEELGFLRYLKAAKVPL----------------NEFEFSWQKIADIQLQLEKL 576

  Fly   813 LEDDRELHDKSCKAFVSWMKFYSTFPKELKPIFNVRIAHMGHFAKSFALKEAPSKFAAKHAAPKA 877
            :..:..|:..:.:||.|:::.|.:  .:||.||||....:...||||..               .
  Fly   577 IAKNYFLNQSAKEAFKSYVRAYDS--HQLKQIFNVNTLDLQAVAKSFGF---------------L 624

  Fly   878 APPTNRLTYTERDPEKIQAQKRAKRRFTTTVSGEVRQLQQRDVGAQKPGAPPPKGGFIGGGVGRS 942
            .||...|                                  .|||.|...|..:.|  |||.|
  Fly   625 VPPVVDL----------------------------------KVGAAKRERPEKRVG--GGGFG-- 651

  Fly   943 SFMKSLGKSRALNMSEF 959
             |.|.:.:..|.....|
  Fly   652 -FYKKMNEGSASKQRHF 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8611	NP_788922.1	DUF2413	203..>285	CDD:287302	19/92 (21%)
		P-loop_NTPase	332..548	CDD:304359	83/218 (38%)
		DEXDc	348..554	CDD:214692	87/211 (41%)
		HELICc	601..757	CDD:238034	51/156 (33%)
		DUF4217	805..866	CDD:290667	17/60 (28%)
pit	NP_001287459.1	SrmB	186..677	CDD:223587	189/664 (28%)
		DEADc	187..394	CDD:238167	89/246 (36%)
		HELICc	408..537	CDD:238034	52/160 (33%)
		DUF4217	569..627	CDD:290667	17/74 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451630
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950