DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8611 and CG7483

DIOPT Version :9

Sequence 1:	NP_788922.1	Gene:	CG8611 / 32725	FlyBaseID:	FBgn0027602	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_649788.2	Gene:	CG7483 / 40987	FlyBaseID:	FBgn0037573	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	510	Identity:	120/510 - (23%)
Similarity:	214/510 - (41%)	Gaps:	144/510 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 AKKPPKAEETSSTNRFRTKKIGLFDQSDVEALKQLGQRAVKPVKETIFTGSKISTLGLHPHAVKN 341
            |:|..:||:.|:. .|.|.:       |||.:....   ...:||.:..|  |...|
  Fly     2 ARKNAQAEDLSNV-EFETSE-------DVEVIPTFN---AMNLKEELLRG--IYAYG-------- 45

  Fly   342 LEDLLSIRELTSVQQKTIPEVLQGKDVLVRSQTGSGKTLAYALPLVELLQKQQPRIQRKDGVLAL 406
                  ..:.:::||::|..:::|:||:.::|:|:|||..:::.:::.|.......|      .|
  Fly    46 ------FEKPSAIQQRSITPIVKGRDVIAQAQSGTGKTATFSISILQSLDTTLRETQ------VL 98

  Fly   407 VIVPTRELVMQTYELIQKLVKPYTWIVPGSL--------LGGESRKSEKARLRKGINILIGTPGR 463
            .:.|||||.:|    |||::     :..|.:        :||.:...:..:|..|.:|:.|||||
  Fly    99 CLSPTRELAVQ----IQKVI-----LALGDMMNVQCHVCIGGTNLGEDIRKLDYGQHIVSGTPGR 154

  Fly   464 LVD----HLLHTASFKLTKLQFLILDEADRLLELGYERDVKQLVEAIDKQRAECEDKELPQLQRM 524
            :.|    .:|.|.:.|:     |:|||||.:|..|::..:..:...:.           |..|.:
  Fly   155 VFDMIKRRVLRTRAIKM-----LVLDEADEMLNKGFKEQIYDVYRYLP-----------PATQVV 203

  Fly   525 LLSATLTSQVQQLAGLTLKNPLYIDNSDEAASAALKSKDGYQKETIE---ALLEVDDGLGEYQED 586
            |:||||..::.::....:.:|:.|          |..:|....|.|:   ..:|.::...:...|
  Fly   204 LISATLPHEILEMTSKFMTDPIRI----------LVKRDELTLEGIKQFFVAVEREEWKFDTLCD 258

  Fly   587 VTGVLSIPENLQLSYVVVPPKLRLVALSSLLAKEVDASPKQFKAIVFMSTTEMVNFHHDMLNEAL 651
            :...|:|.:                                  |::|.:|...|::..:.:.||
  Fly   259 LYDTLTITQ----------------------------------AVIFCNTKRKVDWLTEKMREA- 288

  Fly   652 TRRVLDEEDEQEKGDSDDDGDIPLLQGLRFFKLHGSMTQTERQGVFRGFRDCASCVLLATDVVGR 716
                                      ......:||.|.|.||..:.:.||...|.||:.|||..|
  Fly   289 --------------------------NFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWAR 327

  Fly   717 GIDVPDIKLVVQYTPPQTTADFVHRVGRTARAGRKGRAVLFLTPSEAQFVRHLEK 771
            ||||..:.||:.|..|.....::||:||:.|.||||.|:.|:...:.:.:|.:|:
  Fly   328 GIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQ 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8611	NP_788922.1	DUF2413	203..>285	CDD:287302	3/7 (43%)
		P-loop_NTPase	332..548	CDD:304359	55/227 (24%)
		DEXDc	348..554	CDD:214692	55/217 (25%)
		HELICc	601..757	CDD:238034	39/155 (25%)
		DUF4217	805..866	CDD:290667
CG7483	NP_649788.2	PTZ00424	4..399	CDD:185609	119/508 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451632
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930