Protein Alignment CG8611 and ais

DIOPT Version :10

• Sequence 1: NP_788922.1
• Gene: CG8611 / 32725
• FlyBaseID: FBgn0027602
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_649009.1
• Gene: ais / 39979
• FlyBaseID: FBgn0036754
• Length: 594
• Species: Drosophila melanogaster
• Alignment Length: 707
• Identity: 179/707 - (25%)
• Similarity: 274/707 - (38%)
• Gaps: 182/707 - (25%)

  Fly   169 KSNKKPKNPNQL-PTPGDLFRAQLEEERRQKRREEGGGDQEASADEEDAKNNSGGGSPRVKPSSA 232
            ||.|:|.:..|| |.|                        |.|..||..|:
  Fly    19 KSKKEPSSKQQLQPLP------------------------EVSKHEEPVKS-------------- 45

  Fly   233 VKESKKSSDIEDSGESGEESATSDEEPDESSAQSPGQEKEPKQTAKKPPKAEETSSTNRFRTKKI 297
                             |||...||:..|..........:||   :|.||.|:|.|......:|.
  Fly    46 -----------------EESDKDDEDITEFRLLDGDSSNQPK---RKKPKKEKTLSPKELEIQKA 90

  Fly   298 GLFDQSDVEALKQLGQRA----VKPVKETIFTGSKISTLGLHPHAVKNLEDLLS--IRELTSVQQ 356
            .   :...|..||.|.|.    |.|..::.  |:......:.|...:|   |||  ....|.:|.
  Fly    91 A---EEANETRKQYGIRVLGKNVPPPVDSF--GTLTRDFKMLPRLQQN---LLSRNFDHPTPIQM 147

  Fly   357 KTIPEVLQGKDVLVRSQTGSGKTLAYALPLVELLQKQQPRIQRKDGVLALVIVPTRELVMQTYEL 421
            :.:|.:||.:.::..:.||||||||:..|::..|     |..:..|:.|||:.|||||..|.|..
  Fly   148 QALPVLLQRRALMACAPTGSGKTLAFLTPIINGL-----RAHKTTGLRALVLAPTRELAQQIYRE 207

  Fly   422 IQKLVKPYTWIVPGSLLGGESRKSEKARLRKGINILIGTPGRLVDHLLHTAS--FKLTKLQFLIL 484
            ..:|.:.............|:::...|..::..:||:.||.| |..||....  ..|:.:::.:|
  Fly   208 CAELTRETGLRTHFISKVSEAKQKHGAECKQRYDILVSTPNR-VRFLLQQEPPLLDLSHVEWFVL 271

  Fly   485 DEADRLLELGYERDVKQLVEAIDKQRAECEDKELPQLQRMLLSATLTSQVQQLAGLTLKNPLYID 549
            ||||||:|.|.....:||    |...|.|.:   |.......|||.|..|.:.|...|||
  Fly   272 DEADRLMEEGQNNFKEQL----DDIYAACSN---PTKCVAFFSATYTVPVAKWALRHLKN----- 324

  Fly   550 NSDEAASAALKSKDGYQKETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPK-LRLVAL 613
                                   |:.:..|:   |...|      |.:|...:.|..: .:|||:
  Fly   325 -----------------------LVRITIGV---QNSAT------ETVQQELLFVGSEGGKLVAI 357

  Fly   614 SSLLAKEVDASPKQFKAIVFMSTTEMVNFHHDMLNEALTRRVLDEEDEQEKGDSDDDGDIPLLQG 678
            ..|:.:.:     |...:||:.:.|...    .|.|.|                       |..|
  Fly   358 RDLVRQGL-----QPPVLVFVQSKERAK----QLFEEL-----------------------LYDG 390

  Fly   679 LRFFKLHGSMTQTERQGVFRGFRDCASCVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHRVG 743
            :....:|...:|.:|....:.||:.:..||:.|:::|||||...:.||:.|..|.||..::||:|
  Fly   391 INVDVIHAERSQHQRDNCVKAFREGSIWVLICTELMGRGIDFKGVNLVINYDFPPTTISYIHRIG 455

  Fly   744 RTARAGRKGRAVLFLTPSEAQFVR----------------HLEKKRIRIQQGDMYAYLQTLLPKD 792
            ||.||||.|||:.|.|..:...:|                .|:.|::|..:..|.|  :..|.::
  Fly   456 RTGRAGRPGRAITFFTQEDTSNLRGIALIIKNSGGTVPEYMLQMKKVRKSEAKMRA--KKPLDRE 518

  Fly   793 DEARTVQ-EAASNLQHKFQTLLEDDR-ELHDKSCKAFV----SWMKFYSTFPKELKP 843
            |.:..:: |...:.:||...|.:.:| |...|:.|.:.    |..|.......||||
  Fly   519 DISTKIRPETKGDEKHKSTKLKKVERTEKILKNRKGYEKDLNSKQKKLGNIKTELKP 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8611	NP_788922.1	PTZ00108	<6..263	CDD:240271	19/94 (20%)
		PRK11776	330..>770	CDD:236977	122/460 (27%)
		DEADc_DDX31	339..549	CDD:350707	67/213 (31%)
		DUF4217	806..866	CDD:464056	13/43 (30%)
ais	NP_649009.1	SrmB	123..538	CDD:440279	132/501 (26%)