Protein Alignment CG8611 and Ddx24

DIOPT Version :9

• Sequence 1: NP_788922.1
• Gene: CG8611 / 32725
• FlyBaseID: FBgn0027602
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_954550.1
• Gene: Ddx24 / 373065
• RGDID: 727929
• Length: 851
• Species: Rattus norvegicus
• Alignment Length: 985
• Identity: 215/985 - (21%)
• Similarity: 358/985 - (36%)
• Gaps: 337/985 - (34%)

  Fly   135 KAKPKITRAERLGKKQRQG-KPLTKLSEEQIT-----------------RALKSNKKPKNPNQLP 181
            |:|||  .|.| |..||:| |.:.|.  :|:|                 ..|...:..|||::|
  Rat     7 KSKPK--SASR-GTFQRKGIKVVGKW--KQVTIDPNLFADGQMDDLVCFEELTDYRLVKNPSRL- 65

  Fly   182 TPGDLFRAQLEEERRQKRREEGGGDQEASADEEDAKNNSGGGSPRVK-----PSSAVKESKKSSD 241
                     ..:|..:||:.     |..|.:||:.:..|.....::|     .:..|.|...:.|
  Rat    66 ---------FSDETTKKRKA-----QAVSEEEEEEEGESSSPKKKIKLKKQRDAILVAEGSAAQD 116

  Fly   242 -----IEDSGESGEESATSDEE----PDESSAQSPGQEKEPK---------QTAKKPPKAEETSS 288
                 ..:.|..||.:..||::    ..||.||:..::|:.|         .||.|.||..:|..
  Rat   117 ECEGKASEPGAQGEITVCSDQKVGGATSESLAQTVPRKKKNKGKKKLDTFQSTAPKVPKKAKTWM 181

  Fly   289 TNRFRTKKIGLFDQ-SDVEALKQLGQRAVKPVKETIFTGSKISTLGLHPHAVKNLEDLLSIRELT 352
            ..        :.|| :||.|.:.|                      ..|.||......|.....|
  Rat   182 PE--------VQDQKADVSAWRDL----------------------FVPKAVLRALSFLGFSAPT 216

  Fly   353 SVQQKTIPEVLQGK-DVLVRSQTGSGKTLAYALPLV-ELLQKQQ-------------PRIQR--- 399
            .:|..|:...::.| |:|..::||||||||:|:|:: .:||..:             ||:..
  Rat   217 PIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHSVLQWHKMKAPPIPSSAGVPPRLGAAAH 281

  Fly   400 -----KDG--------------------------------------------------------- 402
                 |||
  Rat   282 RGSPCKDGAKSGVLPEEATIETEAQPSDSGVQATAKAGASAASAQAGLFCDDDAGEGPSSLVEEK 346

  Fly   403 -----------------------------------VLALVIVPTRELVMQTYELIQKLVKPYTWI 432
                                               :|.||:.|||||.:|..:.|..:.| :|.|
  Rat   347 QSKDREEKLDEEQAGKLKQELCDQIAVYKVHPRRPLLGLVLTPTRELAVQVRQHIDAVAK-FTGI 410

  Fly   433 VPGSLLGGESRKSEKARLRKGINILIGTPGRLVDHL--LHTASFKLTKLQFLILDEADRLLELGY 495
            ....|:||.|.:.::..|.:...|:|.|||||.:.:  .|.....|.:|:.|::|||||::|..:
  Rat   411 NTAILVGGMSTQKQQRMLNRHPEIVIATPGRLWELIKEKHPHLSNLRQLRCLVIDEADRMVEKDH 475

  Fly   496 ERDVKQLVEAIDKQRAECEDKELPQLQRMLLSATLTSQVQQLAGLTLKNPLYIDNSDEAASA-AL 559
            ..::.||:|.::      :.:..|..|.::.|||||...|..|.:..|.  ::...|:.|.. .|
  Rat   476 FAELSQLLEMLN------DSQYNPNRQTLVFSATLTLVHQAPARILHKK--HVKKMDKTAKLDLL 532

  Fly   560 KSKDGYQ-----------KETIEALLEVDDGLGEYQEDVTGVLSIPENLQLSYVVVPPKLRLVAL 613
            ..|.|.:           :.|:|.|.|........::|          |.|.|.::
  Rat   533 MQKIGMRGKPKVIDLTRNEGTVETLTETKIHCETDEKD----------LYLYYFLM--------- 578

  Fly   614 SSLLAKEVDASPKQF--KAIVFMSTTEMVNFHHDMLNEALTRRVLDEEDEQEKGDSDDDGDIPLL 676
                         |:  :::||.::...:.....:|      :|||              .:||
  Rat   579 -------------QYPGRSLVFANSISCIKRLSGLL------KVLD--------------IMPL- 609

  Fly   677 QGLRFFKLHGSMTQTERQGVFRGFRDCASCVLLATDVVGRGIDVPDIKLVVQYTPPQTTADFVHR 741
                  .||..|.|.:|......|.....||||||||..||:|:|.::.|:.|..|:|:..::||
  Rat   610 ------TLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYIHR 668

  Fly   742 VGRTARAGRKGRAVLFLTPSEAQFVRHLEKKRIRIQQGDMY----AYLQTLLPKDDEARTVQEAA 802
            .||||||..:|.:::.:.|.:....:.:.|...:.:...::    .|:..:..:...||.:::|.
  Rat   669 SGRTARATSEGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQSKYMDMVKERIRLARQIEKAE 733

  Fly   803 SNLQHKFQTLLED----------DRELHDKSCKAFVSWMKFYSTFPKELKPIFNVRIAHMGHFAK 857
               ...||..|.:          :.||.::..|...:..:......|::| |....:.|:
  Rat   734 ---YRNFQACLHNSWIEQAAAALEIELEEEMYKGGKADQQEERRRQKQMK-ILKQELRHL----- 789

  Fly   858 SFALKEAPSKFAAKHAAPKAAPPTNRLTYTERDPEKIQAQKRAKRRFTTTVSGEVRQLQQRDVGA 922
               |.:...:...|...|         |.:.|.|:.:.    |.|...:.:|...||.::|
  Rat   790 ---LSQPLFQENLKTRYP---------TQSGRPPQPVV----APRNVESALSCLSRQKRRR---- 834

  Fly   923 QKP---GAPP 929
            :||   .|||
  Rat   835 KKPKEHQAPP 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8611	NP_788922.1	DUF2413	203..>285	CDD:287302	25/104 (24%)
		P-loop_NTPase	332..548	CDD:304359	75/332 (23%)
		DEXDc	348..554	CDD:214692	72/322 (22%)
		HELICc	601..757	CDD:238034	41/157 (26%)
		DUF4217	805..866	CDD:290667	11/70 (16%)
Ddx24	NP_954550.1	SrmB	191..735	CDD:223587	137/636 (22%)
		P-loop_NTPase	194..505	CDD:304359	71/339 (21%)
		Helicase_C	567..675	CDD:278689	41/166 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010