Protein Alignment B-H1 and BARX2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_003649.2
• Gene: BARX2 / 8538
• HGNCID: 956
• Length: 279
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 75/316 - (23%)
• Similarity: 102/316 - (32%)
• Gaps: 130/316 - (41%)

  Fly    52 HSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSGGS 116
            |:...:||.|....|    :.....|||::||:......|.|...:
Human     4 HAELRLSSPGQLKAA----RRRYKTFMIDEILSKETCDYFEKLSLY------------------- 45

  Fly   117 SPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQP-HPPT-HPHTHPHALMHPHGK----LGHF 175
                                    .|.||.:..|:| |..| .|....:.|:....:    :.|.
Human    46 ------------------------SVCPSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHL 86

  Fly   176 PPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGL 240
            .|...|    :||   |:..|....|.:|.|                            .||..|
Human    87 VPATPG----IAQ---ALSCHQVTEAVSAEA----------------------------PGGEAL 116

  Fly   241 APPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTA 305
            |         ||:                                 ..|...:...||.|::||.
Human   117 A---------SSE---------------------------------SETEQPTPRQKKPRRSRTI 139

  Fly   306 FTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVG 361
            ||:.||..|||.|::|||||..:|.:||..|.|:..||||||||||.|||:....|
Human   140 FTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKG 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	33/55 (60%)
BARX2	NP_003649.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..137		11/96 (11%)
		Homeodomain	134..190	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..279		1/2 (50%)