Protein Alignment B-H1 and nkx2.1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_571851.1
• Gene: nkx2.1 / 81883
• ZFINID: ZDB-GENE-010404-1
• Length: 346
• Species: Danio rerio
• Alignment Length: 337
• Identity: 87/337 - (25%)
• Similarity: 136/337 - (40%)
• Gaps: 74/337 - (21%)

  Fly   181 GNGLN--VAQY------AAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGG 237
            ||.|.  :|.|      .||||||:       ...|....||....||..:.::...:.|..:|.
Zfish    31 GNNLGAPLASYRQPQVTQAAMQQHH-------MGHNGTVPAAYHMTAAGVSQLSHTAMGGYCNGN 88

  Fly   238 VGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDD----------GNS--VKSGSTS 290
            :       |::.|...|.:       |.....:..|..|.:.|          |:|  :..||.|
Zfish    89 L-------GNMSDLPAYQD-------GMRGSTTATSWYGTNPDPRFSTISRFMGSSSGMNMGSMS 139

  Fly   291 DMSGL-----------SKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVK 344
            .:|.|           |..:||.|..|:..|:..||:.|::|||||..||:.||..:.|:..|||
Zfish   140 TLSSLADVGKGMGPLTSTPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVK 204

  Fly   345 TWYQNRRTKWKRQTAVGL---ELLAEAGNFAAFQRLYGGSPYLGAWPYAA-----AAGAAHGATP 401
            .|:||.|.|.|||....:   ::..:.|:....|:    ||...|.|...     ..|::|  ||
Zfish   205 IWFQNHRYKMKRQAKDKVSQQQMQQDNGSCQQQQQ----SPRRVAVPVLVKDGKPCQGSSH--TP 263

  Fly   402 HTNIDIYYRQAA-------AAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLS 459
            :|.:..::.|..       .:.:|.:.....:.:...|:.:|......|:..:.:...|.|:|..
Zfish   264 NTGVQNHHHQGGNVMFMTNTSLSMSQHQSQQVGSAGQSLDLGQHAASPPSLQTQVPGLSHLNSSG 328

  Fly   460 SYYQSAAAAASA 471
            |.| .||...||
Zfish   329 SEY-GAALPCSA 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	26/55 (47%)
nkx2.1	NP_571851.1	Homeodomain	160..216	CDD:459649	26/55 (47%)