| Sequence 1: | NP_523387.1 | Gene: | B-H1 / 32724 | FlyBaseID: | FBgn0011758 | Length: | 544 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_082292.1 | Gene: | Nanog / 71950 | MGIID: | 1919200 | Length: | 305 | Species: | Mus musculus |
| Alignment Length: | 165 | Identity: | 50/165 - (30%) |
|---|---|---|---|
| Similarity: | 78/165 - (47%) | Gaps: | 41/165 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 238 VGL----APPAGGDLDDSSD-------YHEENEDCDSGNMDDHSVCSNG-------------GKD 278
Fly 279 DDGNSVK---------SGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAH 334
Fly 335 KLDLSDCQVKTWYQNRRTKWKR-------QTAVGL 362 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| B-H1 | NP_523387.1 | Homeodomain | 300..356 | CDD:459649 | 29/55 (53%) |
| Nanog | NP_082292.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..30 | 5/26 (19%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 46..95 | 6/48 (13%) | |||
| Sufficient for interaction with SALL4. /evidence=ECO:0000269|PubMed:16840789 | 96..155 | 31/58 (53%) | |||
| Homeodomain | 98..153 | CDD:459649 | 29/54 (54%) | ||
| Required for DNA-binding. /evidence=ECO:0000250|UniProtKB:Q9H9S0 | 123..152 | 16/28 (57%) | |||
| PTZ00395 | <190..>250 | CDD:185594 | |||
| 10 X repeats starting with a Trp in each unit | 198..247 | ||||
| Sufficient for transactivation activity | 198..247 | ||||
| Sufficient for strong transactivation activity | 248..305 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||