DRSC/TRiP Functional Genomics Resources

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Protein Alignment B-H1 and nkx2.4b

DIOPT Version :10

Sequence 1:NP_523387.1 Gene:B-H1 / 32724 FlyBaseID:FBgn0011758 Length:544 Species:Drosophila melanogaster
Sequence 2:NP_571664.1 Gene:nkx2.4b / 58112 ZFINID:ZDB-GENE-000830-1 Length:307 Species:Danio rerio


Alignment Length:427 Identity:90/427 - (21%)
Similarity:133/427 - (31%) Gaps:175/427 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 FMINDIL---------------AGSAAAAFYKQQQHHQ-QLHHHNNNNNSGSSGGSSPAHSNNNN 125
            |.::|||               :.|.|:..|:|.|..| .|..|:.::|:.....|..:||....
Zfish    11 FSVSDILSPIEETFKKFAAMESSASLASPLYRQSQVSQANLQQHSMSHNAYHMPHSQFSHSTMGG 75

  Fly   126 NINGDNCEASNVAGVGVLPSALH--------------HPQPHPPTHPHTHPHALMHPHGKLGHF- 175
            ..||      .:..:|.|||...              :|:|..||               :..| 
Zfish    76 YCNG------TIGAMGDLPSYQESMRNGATATAWYGSNPEPRYPT---------------ISRFM 119

  Fly   176 PPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGL 240
            .|:||.|                                                       :|.
Zfish   120 GPSAGMN-------------------------------------------------------MGT 129

  Fly   241 APPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTA 305
            .|                                 |.|        .|.|.::..:..:||.|..
Zfish   130 LP---------------------------------GMD--------ASKSMVTLHAAPRRKRRVL 153

  Fly   306 FTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGN 370
            |:..|:..||:.|::|||||..||:.||..:.|:..|||.|:||.|.|.|||.........::||
Zfish   154 FSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKASQQQDSGN 218

  Fly   371 FAAFQRLYGGSPYLGAWPYAAAAG--AAHGA---TP-HTNIDIYYRQAAAAAA----MQKPLPYN 425
            ..|.|     ||...|.|.....|  ..:|:   || |..:.........|:|    ...|.|  
Zfish   219 MCAQQ-----SPRRVALPVLVKDGKPCQNGSGTPTPIHQQVQSVLGSETLASAEDLEEMSPSP-- 276

  Fly   426 LYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYY 462
                 |.:|     |:.....:.:..:||:.|.:..|
Zfish   277 -----PLMG-----GLSQTDAALIEYTSSMVSSNLLY 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
B-H1NP_523387.1 Homeodomain 300..356 CDD:459649 26/55 (47%)
nkx2.4bNP_571664.1 Homeodomain 148..204 CDD:459649 26/55 (47%)

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