Protein Alignment B-H1 and NKX3-2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001180.1
• Gene: NKX3-2 / 579
• HGNCID: 951
• Length: 333
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 71/261 - (27%)
• Similarity: 101/261 - (38%)
• Gaps: 70/261 - (26%)

  Fly   165 LMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAA---AAAAAAARNNAAAAAAAAAAAAAAGVA 226
            |..|.|:     |..||...:||...|........   |.|...|.::..|:.|....||.....
Human    27 LAAPEGR-----PAPGGTAASVAAAPAVCCWRLFGERDAGALGGAEDSLLASPAGTRTAAGRTAE 86

  Fly   227 APP------------------VDGGVDGGVGLAPPAGG---------DLDDSSDYHEENEDCDSG 264
            :|.                  .|.....|.||   |||         :|..|.|..||    .:|
Human    87 SPEGWDSDSALSEENESRRRCADARGASGAGL---AGGSLSLGQPVCELAASKDLEEE----AAG 144

  Fly   265 NMDDHSVCSNGG-----KDDDG------------NSVKSGSTSDMSGLSK----------KQRKA 302
            ..|.....|..|     .:|||            :....|..|..:|:::          :::::
Human   145 RSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRS 209

  Fly   303 RTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAE 367
            |.||:..|:..||:.|..|:|||..||.:||..|.|::.|||.|:||||.|.||: .:..:|||.
Human   210 RAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR-QMAADLLAS 273

  Fly   368 A 368
            |
Human   274 A 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	26/55 (47%)
NKX3-2	NP_001180.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..113		7/47 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..212		13/77 (17%)
		Homeodomain	207..263	CDD:459649	26/55 (47%)