Protein Alignment B-H1 and BARHL1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_064448.1
• Gene: BARHL1 / 56751
• HGNCID: 953
• Length: 327
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 115/289 - (39%)
• Similarity: 147/289 - (50%)
• Gaps: 51/289 - (17%)

  Fly   176 PPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAA-------------AAAAAAAAAGVAA 227
            |..|.|.||:         .|......:|.|::....::             ||.|..:::|..|
Human    66 PGGASGPGLD---------SHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPA 121

  Fly   228 PPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDM 292
            .|..||     .||..|..|..|..|....|...||    ::.|     |::....:.|...|..
Human   122 APEPGG-----RLAAKAAEDFRDKLDKSGSNASSDS----EYKV-----KEEGDREISSSRDSPP 172

  Fly   293 SGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQ 357
            ..| ||.||||||||||||..||:|||||||||||:|.|||..|:|:|.||||||||||||||||
Human   173 VRL-KKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQ 236

  Fly   358 TAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATPHTNIDIYYRQAAAAAAMQKPL 422
            |||||||||||||::|.||:: .|||.  :|.:..:....||.    :.:|...:|...|:|:||
Human   237 TAVGLELLAEAGNYSALQRMF-PSPYF--YPQSLVSNLDPGAA----LYLYRGPSAPPPALQRPL 294

  Fly   423 -PYNLYAGVPSVGVGVGVGVGPAPFSHLS 450
             |..|..|:.      |....|.|...|:
Human   295 VPRILIHGLQ------GASEPPPPLPPLA 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	45/55 (82%)
BARHL1	NP_064448.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90		8/32 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..184		26/86 (30%)
		Homeodomain	179..235	CDD:459649	45/55 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..327		4/13 (31%)