Protein Alignment B-H1 and NKX1-1

DIOPT Version :9

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001277008.1
• Gene: NKX1-1 / 54729
• HGNCID: 24975
• Length: 448
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 124/474 - (26%)
• Similarity: 160/474 - (33%)
• Gaps: 158/474 - (33%)

  Fly   134 ASNVAGVGVLPSALHHPQ----PHPPTHPHTHPHALMHPHGKLGHF-----PPTAGGN------- 182
            ||.....|.:|:....||    |.||. |.......|....:|..|     ||.|..:
Human     3 ASGPEAPGDIPALPPPPQPGSGPAPPA-PAAAAQEAMDGRAELPAFPRAGAPPLAASDTVPAAPE 66

  Fly   183 GLNVAQYAAAMQQ-------------------------HYAAAAAAAAARNNAAAAAAAA----- 217
            |...|:.||.::.                         ..|.||.|..|....|.|.||:
Human    67 GAGAARPAAPLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAASGRPPR 131

  Fly   218 -------AAAAAAGVAA----PP---------------VDGGVDGGVGLAPPA-GGD--LDDSSD 253
                   |.|.|.||.|    ||               .:|...||.|.:|.| .||  .||..|
Human   132 AEELERRALAGAGGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDEDD 196

  Fly   254 YHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMS------------------------- 293
            ..:|..:.::....:.:....||....|:..:..:.:|.|
Human   197 DEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSPVAQGPPG 261

  Fly   294 -----------------------------GLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQER 329
                                         ..|.|.|:||||||..||..||..|:..:||||.||
Human   262 GAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCER 326

  Fly   330 QELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAG 394
            ..||..|.|::.|||.|:||||||||:|.. |.:..|..|.        ||.|..||.|   ..|
Human   327 LNLALSLSLTETQVKIWFQNRRTKWKKQNP-GADTSAPTGG--------GGGPGPGAGP---GTG 379

  Fly   395 AAHGATPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLS 459
            ...|.:|          .:.:..|..||..:..||.|:.|.|..|.....||  ||:.:.||...
Human   380 LPGGLSP----------LSPSPPMGAPLGMHGPAGYPAHGPGGLVCAAQLPF--LSSPAVLSPFV 432

  Fly   460 SYYQSAAAAASAANPGGPH 478
            ...|:..|.|..|    ||
Human   433 LGSQTYGAPAFYA----PH 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeobox	303..355	CDD:278475	30/51 (59%)
NKX1-1	NP_001277008.1	Homeobox	300..352	CDD:278475	30/51 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810