Protein Alignment B-H1 and MSX1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 87/296 - (29%)
• Similarity: 116/296 - (39%)
• Gaps: 73/296 - (24%)

  Fly   177 PTAGGNGLNVAQYAAAMQQHYAAAAAAAAA----------------------------RNNAA-- 211
            |..||.|           |..:||||.|||                            |...|
Human    24 PAGGGAG-----------QAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKE 77

  Fly   212 AAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPA------------GGDLDDSSDYHEENEDCDSG 264
            :|.|.:....|||.:|.|: |...|.:| ||.|            ||.|....|...:.|   |.
Human    78 SALAPSEGVQAAGGSAQPL-GVPPGSLG-APDAPSSPRPLGHFSVGGLLKLPEDALVKAE---SP 137

  Fly   265 NMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQER 329
            ...:.:......:.....:.:....:......|..||.||.||..||..||:.|.:::|||:.||
Human   138 EKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAER 202

  Fly   330 QELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGS-PYLGAWPYAAAA 393
            .|.:..|.|::.|||.|:||||.|.||.....||.|..|.........:|.| |..|....||||
Human   203 AEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAA 267

  Fly   394 GAA-HGAT-PHTNIDIYYRQAAAAAAMQKPLPYNLY 427
            ||: :||: |       :::||...|     |..||
Human   268 GASLYGASGP-------FQRAALPVA-----PVGLY 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/55 (51%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		12/41 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		15/49 (31%)
		PTZ00449	<105..>248	CDD:185628	44/145 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		3/43 (7%)
		Homeodomain	173..229	CDD:459649	28/55 (51%)