Protein Alignment B-H1 and nkx6.1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Alignment Length: 367
• Identity: 76/367 - (20%)
• Similarity: 115/367 - (31%)
• Gaps: 148/367 - (40%)

  Fly    44 PPAVAHSIHSTTTM-----------SSGGSTTTASGIGKPNRSRFMIND--ILAGSAAAAFYKQQ 95
            ||..|  :||.|.|           |:|.:::|:.....||.....::.  |...|..:|....|
Zfish    20 PPLAA--LHSMTEMKTPLYPAYPLSSTGPASSTSPTATSPNPGGIPVSSPGIKTSSGLSALASAQ 82

  Fly    96 QHHQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHT 160
            |......|..|:..|..|...|||                     |:|..........||..|..
Zfish    83 QCAIATPHGINDILSRPSVACSPA---------------------GILSGLPRFSSLSPPPPPGL 126

  Fly   161 HPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQ----------------HYAAAAAAAAARNN 209
                         :|.|:|.  .:.||:|...:.:                |:..|..|.:...|
Zfish   127 -------------YFSPSAA--AVAVARYPKPLTELPGRTPIFWPGVMQSPHWRDARFACSPHQN 176

  Fly   210 AAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSN 274
            :...
Zfish   177 SVLL------------------------------------------------------------- 180

  Fly   275 GGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLS 339
               |.||                |::..|..|:..|:..|||:||:.|||:..||..||:.|.::
Zfish   181 ---DKDG----------------KRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMT 226

  Fly   340 DCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGS 381
            :.|||.|:|||||||:::.|..: ..|:....:..:||.|.|
Zfish   227 ESQVKVWFQNRRTKWRKRHAAEM-ASAKKKQDSETERLKGAS 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	27/55 (49%)
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	28/57 (49%)