Protein Alignment B-H1 and MEOX2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_005915.2
• Gene: MEOX2 / 4223
• HGNCID: 7014
• Length: 304
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 81/340 - (23%)
• Similarity: 116/340 - (34%)
• Gaps: 115/340 - (33%)

  Fly    35 QHHLHYGLQPP-AVAHSIH--STTTMSSGG----------STTTASGI--GKPNRSRFMINDILA 84
            :|.|...|:.| |.|..:|  |.::::..|          ||:::|.|  |.||..
Human     2 EHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEE--------- 57

  Fly    85 GSAAAAFYKQQQHHQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHH 149
            |..|:..::...||...|||::             |....:.               .|.:..|.
Human    58 GMFASQHHRGHHHHHHHHHHHH-------------HQQQQHQ---------------ALQTNWHL 94

  Fly   150 PQPHPPTHPHTHPHALMHPHG---KLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAA 211
            ||...|.....|...|....|   :||..||....|                         :::.
Human    95 PQMSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSN-------------------------SSSL 134

  Fly   212 AAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGG 276
            .::....||.|.|          |.|.....||..:.........::.|...||.
Human   135 GSSTPTGAACAPG----------DYGRQALSPAEAEKRSGGKRKSDSSDSQEGNY---------- 179

  Fly   277 KDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDC 341
                           .|.::.|.||.|||||..|::.||..|....||:...|.|:|..|||::.
Human   180 ---------------KSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTER 229

  Fly   342 QVKTWYQNRRTKWKR 356
            |||.|:||||.||||
Human   230 QVKVWFQNRRMKWKR 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	29/55 (53%)
MEOX2	NP_005915.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..192		34/216 (16%)
		COG5576	160..284	CDD:227863	36/110 (33%)
		Homeodomain	188..244	CDD:459649	29/55 (53%)