Protein Alignment B-H1 and NKX1-2

DIOPT Version :9

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001139812.1
• Gene: NKX1-2 / 390010
• HGNCID: 31652
• Length: 310
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 87/318 - (27%)
• Similarity: 116/318 - (36%)
• Gaps: 89/318 - (27%)

  Fly   195 QHYAAAAAAAA------ARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPP-AGGDLDDSS 252
            |.:..||..|.      ||.:.|...|...|::...|...........|.|.|.| .|.:.::..
Human    29 QKFTRAALPAVRPAPREARKSLAEVEAGKDASSRDPVRQLETPDAAGPGAGQASPLEGSEAEEEE 93

  Fly   253 DYHE------------------ENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSK-- 297
            |..:                  .:.|..:|.:.....|.:||    |..|:|...|..|...:
Human    94 DAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGG----GGPVRSPPGSPGSPRPRRR 154

  Fly   298 -------KQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWK 355
                   |.|:||||||..||..||..|...:||||.||..||..|.|::.|||.|:||||||||
Human   155 RLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWK 219

  Fly   356 RQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATPHTNIDIYYRQAAAAAAMQK 420
            :|.. |.:..|:.|         ||:|..||  .....|...|.:|
Human   220 KQNP-GADGAAQVG---------GGAPQPGA--AGGGGGGGSGGSP------------------- 253

  Fly   421 PLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAA-AASAANPGGP 477
                    |.|..|.           .|.....|.|:.:..:.|||: ..:||.||.|
Human   254 --------GPPGTGA-----------LHFQTFPSYSAANVLFPSAASFPLTAAAPGSP 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeobox	303..355	CDD:278475	30/51 (59%)
NKX1-2	NP_001139812.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..165		24/132 (18%)
		Homeobox	167..219	CDD:278475	30/51 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..260		17/81 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810