Protein Alignment B-H1 and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 342
• Identity: 100/342 - (29%)
• Similarity: 134/342 - (39%)
• Gaps: 77/342 - (22%)

  Fly   162 PHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVA 226
            |..|..|.|...:..|..|.:  :.|...|.||..:|.|...||    ||||||||||||||...
  Rat    35 PPGLGAPLGAAAYRAPPTGPS--SQAAAVAGMQPPHAMAGHNAA----AAAAAAAAAAAAAATYH 93

  Fly   227 APP-------------VDGGVDGGVGLAPP-----AGGDLDDSSDYHEENEDCDSGNMDDHSVCS 273
            .||             .:||: |.:|..|.     .||....::.::..|.|....     |:..
  Rat    94 MPPGVSQFPHSAMGSYCNGGL-GNMGELPAYTDGMRGGAAAAATGWYGANTDPRYS-----SISR 152

  Fly   274 NGGKDDDGNSVKSGSTSDMSGLSKK---------QRKARTAFTDHQLQTLEKSFERQKYLSVQER 329
            ..|.....|....||.:.::..:|.         :||.|..|:..|:..||:.|::|||||..||
  Rat   153 FMGPSAGVNVAGMGSLTGIADAAKSLAPLHAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPER 217

  Fly   330 QELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAG 394
            :.||..:.|:..|||.|:||.|.|.|||          |.:.||.|....|.  ||..|......
  Rat   218 EHLASMIHLTPTQVKIWFQNHRYKMKRQ----------AKDKAAQQLQQEGG--LGPPPPPPPPS 270

  Fly   395 AAHGATPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLS 459
            .              |:.|....::...|....||.|:.|.|......|.|      :|.|..||
  Rat   271 P--------------RRVAVPVLVKDGKPCQNGAGTPTPGQGGQQPQAPTP------ASELEELS 315

  Fly   460 SYYQSAAAAASAANPGG 476
            |      :..:...|||
  Rat   316 S------SPPALHGPGG 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	26/55 (47%)
Nkx2-4	XP_038962557.1	Homeodomain	188..244	CDD:459649	26/55 (47%)