Protein Alignment B-H1 and Lim3

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001260559.1
• Gene: Lim3 / 35184
• FlyBaseID: FBgn0002023
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 124/646 - (19%)
• Similarity: 182/646 - (28%)
• Gaps: 271/646 - (41%)

  Fly     8 LTQTPSEPNAAHPQLHHHLSTLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGSTTTASGIGKP 72
            :.||...|    |.||||      ..|||.|.:   ||
  Fly     1 MMQTLKPP----PPLHHH------HQHQHQLQH---PP--------------------------- 25

  Fly    73 NRSRFMINDILAGSAAAAFYKQQQH-HQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGDNCEASN 136
                                :||.| ||||.|              |.....:
  Fly    26 --------------------QQQPHPHQQLQH--------------PLQQQQH------------ 44

  Fly   137 VAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAA 201
                   .||:.:.|.|.|     |.|.......:|   |||...:.|...|.......|:...|
  Fly    45 -------LSAMDNHQQHQP-----HIHQQQQQQQQL---PPTPQASHLVGGQQQQQQHPHHNHLA 94

  Fly   202 A-----------AAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGG----DLD-- 249
            .           |..:||.|..|.                          .|..||    .||
  Fly    95 VDQDDPNPELVLALISRNRALEAT--------------------------IPKCGGCHELILDRF 133

  Fly   250 --------------DSSDYHEENED-------------------------CDSG--------NMD 267
                          ..|:.|.:..|                         ||.|        ...
  Fly   134 ILKVLERTWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSACDMGIPPTQVVRRAQ 198

  Fly   268 DH---------SVCS---NGGKD----DDGNSV--KSGSTSDMSGL--------SKKQRKARTAF 306
            |:         ::||   |.|.:    :|...:  :....:...||        .:..::.||..
  Fly   199 DNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEEAKAKGLYLDGSLDGDQPNKRPRTTI 263

  Fly   307 TDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGN- 370
            |..||:||:.::......:...|::|:....|....|:.|:||||.|.||       |..:||.
  Fly   264 TAKQLETLKTAYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKR-------LKKDAGRT 321

  Fly   371 --FAAFQRLYGG-SPY---------------------LGAWPYAAA-AGAAHGATPHTNIDIYYR 410
              ...|:.:.|. ||.                     |....|:.. .|...||:|| :|...|.
  Fly   322 RWSQYFRSMKGNCSPRTDKFLDKDELKVDYDSFSHHDLSNDSYSTVNLGLDEGASPH-SIRGSYM 385

  Fly   411 QAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHL----SASSSLSSLSSYYQ--SAAAAA 469
            ..:::.:...|..    ...|.||.|...|..|....:.    :..|||.:..::::  |:...:
  Fly   386 HGSSSPSQYPPSS----RSPPPVGQGHTFGSYPDNIVYTNIDQAVGSSLHASKAHHRLHSSNNVS 446

  Fly   470 SAANPGGP---HPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPG 527
            ..:|...|   :|..||      ||.|.|......::.||:......|:.|...|..|..|
  Fly   447 DLSNDSSPDQGYPDFPP------SPDSWLGDSGSTNTTSANNNANNNSSSSHNNNNSSGGG 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	17/55 (31%)
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754	7/50 (14%)
		LIM2_Lhx3_Lhx4	181..236	CDD:188762	9/54 (17%)
		Homeodomain	257..313	CDD:459649	17/55 (31%)