Protein Alignment B-H1 and B-H2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_523386.1
• Gene: B-H2 / 32723
• FlyBaseID: FBgn0004854
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 700
• Identity: 257/700 - (36%)
• Similarity: 313/700 - (44%)
• Gaps: 236/700 - (33%)

  Fly     1 MKDSMSILTQTP--SEPNAAHPQLHHHLSTLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGST 63
            |...||..|..|  |.|:|.                .||      |.||...:....:.:.|.:|
  Fly     4 MPPEMSATTAAPVGSAPSAT----------------AHH------PAAVGGGMPRPASPAVGSNT 46

  Fly    64 TTASGIGKPNRSRFMINDILAGSAAA------------------------------AFYKQQQHH 98
            |||:.. ...||||||.|||||:|||                              :...|..||
  Fly    47 TTATAT-TATRSRFMITDILAGAAAASAAAAAAAAALAAASSGGGRGSPTDSEREQSLVAQHHHH 110

  Fly    99 ---QQLHHHNNNNNSGSSGGSSP------------------------AHSNNNNNINGDNCEASN 136
               ||.|||:...........:.                        .|....::..|:|
  Fly   111 HQQQQQHHHHQQQQQQQQHQQAALQQYIVQQQQLLRFEREREREREREHYRERHSPPGNN----- 170

  Fly   137 VAGVGVLPSALHHPQP------HPPTH--------------PHTHPHALM-----------HPHG 170
                   |.| |||.|      .||.|              .|.|||.|.           |.||
  Fly   171 -------PYA-HHPMPPHLLAHFPPAHYAVLQQQQQQQQQQQHPHPHHLQLERERLEALHRHGHG 227

  Fly   171 KLG---------------------HFP------------PTAGGNGLNVAQYAAAMQQHYAAAAA 202
            ..|                     |.|            ...||||.|      ....:..:::|
  Fly   228 LTGDPAQHLSHLSHLSHQQHHPHLHHPMHDERSRSPLMLQQLGGNGGN------NNNNNNNSSSA 286

  Fly   203 AAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPA---GGD----LDDSSDYHEENED 260
            :....||..:|:|.:...:....::...:|..:|.:.|..|.   .||    :|||     :::|
  Fly   287 SNNNNNNNNSASANSNIISGNSSSSNNNNGSGNGNMLLGGPGSSISGDQASTIDDS-----DSDD 346

  Fly   261 CDSGNMDDHSVCSNGGKDDDG-NSVKSGSTS--DMS-----GLSKKQRKARTAFTDHQLQTLEKS 317
            |             ||||||| :|:|:||::  |.|     .|||||||||||||||||||||||
  Fly   347 C-------------GGKDDDGDDSMKNGSSANGDSSSHLSLSLSKKQRKARTAFTDHQLQTLEKS 398

  Fly   318 FERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGG-S 381
            ||||||||||:|.|||:||:|||||||||||||||||||||||||||||||||:||||||||| :
  Fly   399 FERQKYLSVQDRMELANKLELSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNYAAFQRLYGGAT 463

  Fly   382 PYLGAWPYAAAAGA--AHGATPHTNIDIYYRQAAAAAAMQKP-LP--YNLYAGVPSVGVGVGVGV 441
            |||.||||||||.|  .||||| :.||||||||||||||||| ||  |.:|..  |:..|:.:..
  Fly   464 PYLSAWPYAAAAAAQSPHGATP-SAIDIYYRQAAAAAAMQKPSLPASYRMYQS--SIPPGMSLPG 525

  Fly   442 GPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASA 506
            .|||    ....:...||.||  |||||:||:.|.......||:....          ||.|.||
  Fly   526 MPAP----PPPGAAPMLSGYY--AAAAAAAASAGAQQQQQQPPAASRS----------PATSQSA 574

  Fly   507 SPP---PRPPS-------TPSPTLNPGSPPGR---SVDSCSQSDDEDQIQ 543
            :..   .|..|       ||||.|||||||.|   :.:...:.|:|..|:
  Fly   575 NSEADCERTSSSSRQRLITPSPPLNPGSPPHRERINEEEDRERDEERDIE 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	51/55 (93%)
B-H2	NP_523386.1	Homeodomain	381..437	CDD:459649	51/55 (93%)