Protein Alignment B-H1 and HOXD12

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 68/244 - (27%)
• Similarity: 98/244 - (40%)
• Gaps: 59/244 - (24%)

  Fly   141 GVLPSALHHPQPHPPTHP--------HTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHY 197
            |.||.|. .|....|..|        .:.|:  :...|.||..||||.......|::       |
Human    47 GALPWAA-TPASCAPAQPAGATAFGGFSQPY--LAGSGPLGLQPPTAKDGPEEQAKF-------Y 101

  Fly   198 AAAAAAA---AARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENE 259
            |..|||.   ..|...:.|..::.|.|.|.:.|...|   ..|||.|.|.
Human   102 APEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYD---YAGVGRATPG--------------- 148

  Fly   260 DCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSK-----------------KQRKARTAFT 307
               |..:...:.|:.|.|||....:....|...:|::.                 :.||.|..:|
Human   149 ---STTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYT 210

  Fly   308 DHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKR 356
            ..|:..||..|...::::.|:|:||:::|:|||.|||.|:||||.|.||
Human   211 KQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	25/55 (45%)
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		6/19 (32%)
		Homeodomain	203..259	CDD:459649	25/55 (45%)