Protein Alignment B-H1 and HOXD11

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_067015.2
• Gene: HOXD11 / 3237
• HGNCID: 5134
• Length: 338
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 72/309 - (23%)
• Similarity: 105/309 - (33%)
• Gaps: 113/309 - (36%)

  Fly   144 PSALHHPQPHPPTHPHTHPHALMHPH--------------------------------GKLGHFP 176
            ||.|..|.....|.|::   :.:.||                                |..|..|
Human    32 PSFLSQPSSCQMTFPYS---SNLAPHVQPVREVAFRDYGLERAKWPYRGGGGGGSAGGGSSGGGP 93

  Fly   177 PTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPP------------ 229
               ||.|.....||    .:||||||       ||||||||..||......||
Human    94 ---GGGGGGAGGYA----PYYAAAAA-------AAAAAAAAEEAAMQRELLPPAGRRPDVLFKAP 144

  Fly   230 -----VDGGVDGGVGLA------------------------------------PPAGGDLDDSSD 253
                 ..|...|..|.|                                    |||....:.::|
Human   145 EPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAAD 209

  Fly   254 YHEENEDCDSG----------NMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLS-KKQRKARTAFT 307
            ..:.......|          ..:........|.|.:|...::|:....|.:: ::.||.|..:|
Human   210 KGDPRTGAGGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYT 274

  Fly   308 DHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKR 356
            .:|::.||:.|....|::.::|.:|:..|:|:|.|||.|:||||.|.|:
Human   275 KYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	23/55 (42%)
HOXD11	NP_067015.2	DUF3528	26..185	CDD:432284	38/169 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..270		12/90 (13%)
		Homeodomain	267..323	CDD:459649	23/55 (42%)