Protein Alignment B-H1 and HOXD8

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_062458.1
• Gene: HOXD8 / 3234
• HGNCID: 5139
• Length: 290
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 66/242 - (27%)
• Similarity: 89/242 - (36%)
• Gaps: 79/242 - (32%)

  Fly   174 HFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDG-GVDGG 237
            ||.|..||             :|.|||||.....|:||....|...|.|....:||..| |..|.
Human    35 HFAPEVGG-------------RHAAAAAALQLYGNSAAGFPHAPPQAHAHPHPSPPPSGTGCGGR 86

  Fly   238 VGLA-------------------------------PPAGG--------------DLDDSSDYHEE 257
            .|..                               ||.||              :|.....:..:
Human    87 EGRGQEYFHPGGGSPAAAYQAAPPPPPHPPPPPPPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQ 151

  Fly   258 NE-------DCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQ-----RKARTAFTDHQ 310
            .|       ||.|.:       .|.|:|.| :..:|.|.|.|....:.|     |:.|..::..|
Human   152 QEAELVQYPDCKSSS-------GNIGEDPD-HLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSRFQ 208

  Fly   311 LQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQ 357
            ...|||.|....||:.:.|.|::|.|.|::.|||.|:||||.|||::
Human   209 TLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKE 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	24/55 (44%)
HOXD8	NP_062458.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..127		12/66 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..200		13/46 (28%)
		Homeodomain	198..254	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..290		0/1 (0%)