Protein Alignment B-H1 and HOXD4

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 55/195 - (28%)
• Similarity: 80/195 - (41%)
• Gaps: 38/195 - (19%)

  Fly   166 MHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPV 230
            ::|....|..|  .||:|              ....:|..||.:...........||.|...|
Human    51 LYPRPDFGEQP--FGGSG--------------PGPGSALPARGHGQEPGGPGGHYAAPGEPCP-- 97

  Fly   231 DGGVDGGVGLAPPA--GGDLDDSSDYHEEN-EDCDSGN-MDDHSVCSNGGKDDDGNSVKSGSTSD 291
                      ||||  ...|..:..|.:.: :...||. :...:|.....|....|||....|..
Human    98 ----------APPAPPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGG 152

  Fly   292 MSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKR 356
                  :.:::|||:|..|:..|||.|...:||:.:.|.|:||.|.||:.|:|.|:||||.|||:
Human   153 ------EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKK 211

  Fly   357  356
            Human   212  211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	27/55 (49%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		21/103 (20%)
		Antp-type hexapeptide	133..138		0/4 (0%)
		Homeodomain	155..211	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		55/195 (28%)