Protein Alignment B-H1 and HOXD1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 95/298 - (31%)
• Similarity: 109/298 - (36%)
• Gaps: 74/298 - (24%)

  Fly   128 NGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYA-A 191
            |||.      |.|..||.|...|.|.||..| ..|..           ||.|      ..||| .
Human    45 NGDG------AFVSCLPLAAARPSPSPPAAP-ARPSV-----------PPPA------APQYAQC 85

  Fly   192 AMQQHYAAAAAAAAARNNA-AAAAAAAAAAAAAGVAAPPVDGGVDGG--VGLAPPA----GGD-- 247
            .::..|...||.|||...| .....:..|....||.....|   |||  |..|..|    ||.
Human    86 TLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGVLGRAAD---DGGSHVHYATSAVFSGGGSFL 147

  Fly   248 LDDSSDYHEENED-----CDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGL------------ 295
            |....||....|.     |...:.|.|...........|...|  |.|..|||
Human   148 LSGQVDYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPK--SVSPASGLPAAFSTFEWMKV 210

  Fly   296 ----SKKQRKA-----------RTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKT 345
                |||.:.|           ||.|:..||..|||.|...|||:...|.|:|:.|.|:|.|||.
Human   211 KRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKI 275

  Fly   346 WYQNRRTKWKRQTAVGLELLAEAGNFAAFQ-RLYGGSP 382
            |:||||.|.|::...|  |||.|...|..| .|.|.:|
Human   276 WFQNRRMKQKKREREG--LLATAIPVAPLQLPLSGTTP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/66 (42%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeodomain	233..286	CDD:459649	27/52 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328		3/7 (43%)