Protein Alignment B-H1 and HOXC13

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_059106.2
• Gene: HOXC13 / 3229
• HGNCID: 5125
• Length: 330
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 73/314 - (23%)
• Similarity: 105/314 - (33%)
• Gaps: 108/314 - (34%)

  Fly   111 GSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLGHF 175
            |...|:||..:.:.:.: |.:|.||                         |...|: ||..||.
Human    44 GGCSGASPGKAPSMDGL-GSSCPAS-------------------------HCRDLL-PHPVLGR- 80

  Fly   176 PPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGL 240
            ||         |...|.....|....|..|||..|...|...:::|..|...|  .||...|..|
Human    81 PP---------APLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYP--FGGSYYGCRL 134

  Fly   241 A------------------PPAGGDL--DDSSDYHEE---------NEDCDSGNMD--------- 267
            :                  |...|.|  ||.|...:|         :.....|.:|
Human   135 SHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISG 199

  Fly   268 ---------------DHSVCSNGGKDDDGNSVKSGSTS---------DMSGLS------KKQRKA 302
                           .|...|||. |......|..|.|         |:..|.      ::.||.
Human   200 HPEPRHDALIPVEGYQHWALSNGW-DSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKK 263

  Fly   303 RTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKR 356
            |..:|..||:.|||.:...|:::.::|:.::...:||:.||..|:||||.|.|:
Human   264 RVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	21/55 (38%)
HOXC13	NP_059106.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..50		2/5 (40%)
		HoxA13_N	54..168	CDD:463521	34/152 (22%)
		Homeodomain	261..312	CDD:459649	18/50 (36%)