Protein Alignment B-H1 and HOXC12

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_776272.1
• Gene: HOXC12 / 3228
• HGNCID: 5124
• Length: 282
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 67/244 - (27%)
• Similarity: 94/244 - (38%)
• Gaps: 72/244 - (29%)

  Fly   149 HPQPHPPTHPHTHPHALMHPHGKL----------GHF-PPTA--GGNGLNVAQYAAAMQQHYAAA 200
            :|||:..:     |.:|..|.|:.          |:: .|.|  ||.||...:
Human    64 YPQPYLGS-----PVSLNPPFGRTCELARVEDGKGYYREPCAEGGGGGLKREE------------ 111

  Fly   201 AAAAAARNNAAAAAAAAAAAAAAGVAAPPV----------DGGVDGGVGLAPPAGGDLDDSSDYH 255
                ..|:..|...||......:|   ||.          .||.|||.|..||
Human   112 ----RGRDPGAGPGAALLPLEPSG---PPALGFKYDYAAGGGGGDGGGGAGPP------------ 157

  Fly   256 EENEDCDSGNMDDHSVCSN-----GGKDDDGNSVK--------SGSTSDMSGLSKKQRKARTAFT 307
            .:...|.|...|..|...|     .|..|.|:.|.        |.|.:....::.:.||.|..::
Human   158 HDPPSCQSLESDSSSSLLNEGNKGAGAGDPGSLVSPLNPGGGLSASGAPWYPINSRSRKKRKPYS 222

  Fly   308 DHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKR 356
            ..||..||..|...::::.|.|:||:.:|:|||.|||.|:||||.|.||
Human   223 KLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	25/55 (45%)
HOXC12	NP_776272.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..129		10/50 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..214		18/78 (23%)
		Homeodomain	215..271	CDD:459649	25/55 (45%)