Protein Alignment B-H1 and HOXC10

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_059105.2
• Gene: HOXC10 / 3226
• HGNCID: 5122
• Length: 342
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 57/217 - (26%)
• Similarity: 87/217 - (40%)
• Gaps: 22/217 - (10%)

  Fly   145 SALH-HPQPHPPTHPHTHP----HALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAA 204
            :||: ||.|......|..|    :.....:..|...|..:|.|     .:.|..:|. |:....|
Human   126 AALYSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGAN-----DFEAPFEQR-ASLNPRA 184

  Fly   205 AARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDH 269
            ....:.......:........:..|....:.....||.|.|   ..|....|..:..||.  .|.
Human   185 EHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGPKG---SPSESEKERAKAADSS--PDT 244

  Fly   270 SVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAH 334
            |  .|..|::    :|:.:|:.....:|..||.|..:|.||...|||.|....||:.:.|.|::.
Human   245 S--DNEAKEE----IKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISK 303

  Fly   335 KLDLSDCQVKTWYQNRRTKWKR 356
            .::|:|.|||.|:||||.|.|:
Human   304 TINLTDRQVKIWFQNRRMKLKK 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	25/55 (45%)
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..271		17/94 (18%)
		Homeodomain	269..325	CDD:459649	25/55 (45%)