Protein Alignment B-H1 and HOXC6

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_004494.1
• Gene: HOXC6 / 3223
• HGNCID: 5128
• Length: 235
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 52/248 - (20%)
• Similarity: 91/248 - (36%)
• Gaps: 72/248 - (29%)

  Fly   160 THPHALMHPHGKLGHFPPTAGGNGL--NVAQYAAAMQ--QHYAAAAAAAAARNNAAAAAAAAAAA 220
            |:|....|          .|||..:  |||..:.|..  :|::...||.|.....:....:....
Human     6 TNPSLSCH----------LAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTPFYSPQEN 60

  Fly   221 AAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVK 285
            .....:..|.|.|                 |:.:::|.:           :.||..::..|::.:
Human    61 VVFSSSRGPYDYG-----------------SNSFYQEKD-----------MLSNCRQNTLGHNTQ 97

  Fly   286 SGSTSDMS------------------------------GLSKKQRKARTAFTDHQLQTLEKSFER 320
            :....|.|                              |....:|:.|..::.:|...|||.|..
Human    98 TSIAQDFSSEQGRTAPQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHF 162

  Fly   321 QKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAA 373
            .:||:.:.|.|:|:.|.|::.|:|.|:||||.|||:::.:...|....|...|
Human   163 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATA 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	23/55 (42%)
HOXC6	NP_004494.1	Antp-type hexapeptide	122..127		0/4 (0%)
		Homeodomain	142..198	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..235		3/16 (19%)