Protein Alignment B-H1 and HOXC4

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 68/292 - (23%)
• Similarity: 102/292 - (34%)
• Gaps: 101/292 - (34%)

  Fly   148 HHPQPHPPTHPH-THPH------ALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAA 205
            ||.:.:||..|. ::|.      :|..|....||.|..||
Human    48 HHQELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAG------------------------- 87

  Fly   206 ARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHS 270
             .::...:.:....|..:|.:|.|         ..||||
Human    88 -HHHPEKSQSLCEPAPLSGASASP---------SPAPPA-------------------------- 116

  Fly   271 VCSNGGKDDDGNSVKSG------------STSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKY 323
             ||....|...::....            ||.:.:....:.:::|||:|..|:..|||.|...:|
Human   117 -CSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRY 180

  Fly   324 LSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWP 388
            |:.:.|.|:||.|.||:.|:|.|:||||.|||:.                 .|| ..:....|.|
Human   181 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKD-----------------HRL-PNTKVRSAPP 227

  Fly   389 YAAAAGAAHGATPHTNIDIYYRQAAAAAAMQK 420
            ..||......|||.|:.|  :.|:|.....|:
Human   228 AGAAPSTLSAATPGTSED--HSQSATPPEQQR 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	27/55 (49%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		24/143 (17%)
		Antp-type hexapeptide	135..140		0/4 (0%)
		Homeodomain	157..213	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		14/64 (22%)