Protein Alignment B-H1 and HOXB5

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 77/314 - (24%)
• Similarity: 126/314 - (40%)
• Gaps: 60/314 - (19%)

  Fly    75 SRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSGGSSPAHS-----NNNN---NINGDN 131
            |.:.:|..      :..|.....:|.|::.:.::.|||....:..|:     |.|.   ::|..:
Human     2 SSYFVNSF------SGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS 60

  Fly   132 CEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQH 196
            ..:|:...||....|...|...|.........:|..|..    .|.|.|.:  :.|:.:|:....
Human    61 ASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPES----LPCTNGDS--HGAKPSASSPSD 119

  Fly   197 YAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDC 261
            .|.:|:::|.......|:|::....||...:.|       .:..|.|
Human   120 QATSASSSANFTEIDEASASSEPEEAASQLSSP-------SLARAQP------------------ 159

  Fly   262 DSGNMDDHSVCSNGGKDDDGNSV-----KSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQ 321
                  :....|....:.....:     |...:.||:|...|  :||||:|.:|...|||.|...
Human   160 ------EPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGK--RARTAYTRYQTLELEKEFHFN 216

  Fly   322 KYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQ 375
            :||:.:.|.|:||.|.||:.|:|.|:||||.|||:...:....||.||  :|||
Human   217 RYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAG--SAFQ 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/55 (51%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	23/140 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		20/132 (15%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	29/57 (51%)