Protein Alignment B-H1 and HOXB4

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_076920.1
• Gene: HOXB4 / 3214
• HGNCID: 5115
• Length: 251
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 66/273 - (24%)
• Similarity: 97/273 - (35%)
• Gaps: 67/273 - (24%)

  Fly   154 PPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAA 218
            ||...::....|...|.. |::   |||            |:..::....|.....||......|
Human    18 PPCEEYSQSDYLPSDHSP-GYY---AGG------------QRRESSFQPEAGFGRRAACTVQRYA 66

  Fly   219 AAAAAG-------VAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMD--------- 267
            |....|       ...||...|:.......||||..|.      |..:.|::.:..
Human    67 ACRDPGPPPPPPPPPPPPPPPGLSPRAPAPPPAGALLP------EPGQRCEAVSSSPPPPPCAQN 125

  Fly   268 ------DHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSV 326
                  .||.|...........|.. ||.:.:....:.:::|||:|..|:..|||.|...:||:.
Human   126 PLHPSPSHSACKEPVVYPWMRKVHV-STVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTR 189

  Fly   327 QERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAA 391
            :.|.|:||.|.||:.|:|.|:||||.|||:...:....:...|
Human   190 RRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGG---------------------- 232

  Fly   392 AAGAAHGATPHTN 404
            |||:|.|.....|
Human   233 AAGSAGGPPGRPN 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	27/55 (49%)
HOXB4	NP_076920.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		25/137 (18%)
		Antp-type hexapeptide	141..146		0/4 (0%)
		Homeodomain	163..219	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..251		7/48 (15%)