Protein Alignment B-H1 and HOXB1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_002135.2
• Gene: HOXB1 / 3211
• HGNCID: 5111
• Length: 301
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 69/271 - (25%)
• Similarity: 92/271 - (33%)
• Gaps: 75/271 - (27%)

  Fly   109 NSGSSGG--SSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGK 171
            :.|..||  ||||...|:............|......||. :.|....|::..:..:.|....|.
Human    44 SEGRYGGGLSSPAFQQNSGYPAQQPPSTLGVPFPSSAPSG-YAPAACSPSYGPSQYYPLGQSEGD 107

  Fly   172 LGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDG 236
            .|:|.|::.|                                      |...|::    ||...|
Human   108 GGYFHPSSYG--------------------------------------AQLGGLS----DGYGAG 130

  Fly   237 GVGLAP-----------------PAGGDL---DDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDG 281
            |.|..|                 ||..||   |..:....|.....:...|...|..|..|....
Human   131 GAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTAKV 195

  Fly   282 NSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTW 346
            :....||.|.:          ||.||..||..|||.|...||||...|.|:|..|:|::.|||.|
Human   196 SEPGLGSPSGL----------RTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIW 250

  Fly   347 YQNRRTKWKRQ 357
            :||||.|.|::
Human   251 FQNRRMKQKKR 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/55 (51%)
HOXB1	NP_002135.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..77		9/32 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..149		4/21 (19%)
		Antp-type hexapeptide	179..184		1/4 (25%)
		Homeodomain	207..260	CDD:459649	28/52 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	254..301		4/8 (50%)