Protein Alignment B-H1 and HOXA13

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_000513.2
• Gene: HOXA13 / 3209
• HGNCID: 5102
• Length: 388
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 85/416 - (20%)
• Similarity: 114/416 - (27%)
• Gaps: 233/416 - (56%)

  Fly   106 NNNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHG 170
            |.|..|::..::.|.:           .|:..||.|..|                ||.|
Human    32 NKNMEGAAAAAAAAAA-----------AAAAGAGGGGFP----------------HPAA------ 63

  Fly   171 KLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARN-------------------------NA 210
                  ..|||| .:||..|||     ||||||...||                         :|
Human    64 ------AAAGGN-FSVAAAAAA-----AAAAAANQCRNLMAHPAPLAPGAASAYSSAPGEAPPSA 116

  Fly   211 AAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNG 275
            |||||||||||||..||     ...||.|.|.|||.         |..:.|        |.||..
Human   117 AAAAAAAAAAAAAAAAA-----SSSGGPGPAGPAGA---------EAAKQC--------SPCSAA 159

  Fly   276 GKDDDG-----------------------NSVKS------------------------------- 286
            .:...|                       |::||
Human   160 AQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPAAEEFSSR 224

  Fly   287 ----------------------------------------------------------------- 286
                                                                             
Human   225 AKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQM 289

  Fly   287 ---------------------GSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQ 330
                                 ...||.|.. ::.||.|..:|..||:.||:.:...|:::..:|:
Human   290 YCPKEQAQPPHLWKSTLPDVVSHPSDASSY-RRGRKKRVPYTKVQLKELEREYATNKFITKDKRR 353

  Fly   331 ELAHKLDLSDCQVKTWYQNRRTKWKR 356
            .::...:||:.||..|:||||.|.|:
Human   354 RISATTNLSERQVTIWFQNRRVKEKK 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	20/55 (36%)
HOXA13	NP_000513.2	HoxA13_N	85..224	CDD:463521	34/160 (21%)
		Homeodomain	323..379	CDD:459649	20/55 (36%)