Protein Alignment B-H1 and HOXA10

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 87/401 - (21%)
• Similarity: 124/401 - (30%)
• Gaps: 131/401 - (32%)

  Fly    64 TTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSGGSSPAHSNNNN--- 125
            ||.|....|..:.|:::.:::.....|               .....|:.||....:..:..
Human    16 TTMSCSESPAANSFLVDSLISSGRGEA---------------GGGGGGAGGGGGGGYYAHGGVYL 65

  Fly   126 -----------------NINGDNCEA----SNVAGVGVLPSAL-HHPQP-------------HPP 155
                             .:.|...||    |...|.|:.|.|. :.|.|             .||
Human    66 PPAADLPYGLQSCGLFPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPP 130

  Fly   156 THPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAA 220
            ..|...|.....|..:    ||.......: ..:|..:::..:.....:|.:....:|.||..|.
Human   131 DGPPPPPQQQPPPPPQ----PPQPAPQATS-CSFAQNIKEESSYCLYDSADKCPKVSATAAELAP 190

  Fly   221 AAAGVAAPPVDG---GVDGGV------------GLA---------------------PPAGG-DL 248
            ...|   ||.||   |...||            |.|                     ||..| ||
Human   191 FPRG---PPPDGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDL 252

  Fly   249 -----DDSSDYHEENEDCDSGNMDDHSVCSNGGKDDD-----------------GNSVKSGSTSD 291
                 ..|:|...:....||......:..|.||...|                 ..|.|:....|
Human   253 PPALASGSADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKD 317

  Fly   292 MSGLSKKQ-----------RKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKT 345
            ..|.||.:           ||.|..:|.||...|||.|....||:.:.|.|::..:.|:|.|||.
Human   318 SLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKI 382

  Fly   346 WYQNRRTKWKR 356
            |:||||.|.|:
Human   383 WFQNRRMKLKK 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	25/55 (45%)
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		16/73 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		22/117 (19%)
		Homeodomain	337..393	CDD:459649	25/55 (45%)