Protein Alignment B-H1 and HMX2

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_005510.1
• Gene: HMX2 / 3167
• HGNCID: 5018
• Length: 273
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 77/315 - (24%)
• Similarity: 111/315 - (35%)
• Gaps: 121/315 - (38%)

  Fly   148 HHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAA 212
            |.|:...|.|   ||..   |...|| .|..:||:|
Human    71 HGPKEQGPKH---HPPI---PFPCLG-TPKGSGGSG----------------------------- 99

  Fly   213 AAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGK 277
                              .||::....|:|       ..||:.||.|          .:...|..
Human   100 ------------------PGGLERTPFLSP-------SHSDFKEEKE----------RLLPAGSP 129

  Fly   278 DDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQ 342
            .......:.|.....:|.:||  |.||.|:..|:..||.:|:.::|||..||..||..|.|::.|
Human   130 SPGSERPRDGGAERQAGAAKK--KTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQ 192

  Fly   343 VKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAH-GATPHTNID 406
            ||||:||||.|||||.:..||                            ||..|| .|....::.
Human   193 VKTWFQNRRNKWKRQLSAELE----------------------------AANMAHASAQTLVSMP 229

  Fly   407 IYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSY 461
            :.:|.   ::.::.|:|.:|              ..|||..:  ..|:||:|..|
Human   230 LVFRD---SSLLRVPVPRSL--------------AFPAPLYY--PGSNLSALPLY 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/55 (51%)
HMX2	NP_005510.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		27/153 (18%)
		Homeodomain	150..206	CDD:459649	29/57 (51%)