Protein Alignment B-H1 and HLX

DIOPT Version :9

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 128/544 - (23%)
• Similarity: 187/544 - (34%)
• Gaps: 141/544 - (25%)

  Fly    41 GLQP-PAVAHSIHSTTTMSSGGS-----TTTASGIGKPNRSRFMINDI--------------LAG 85
            ||.| .|...|:.|....||.|.     ....:.:.||:   |.|.||              |||
Human     5 GLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPS---FCIADILHAGVGDLGAAPEGLAG 66

  Fly    86 SAAAAFYKQQQHHQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHP 150
            ::|||.   ..|...:|.|    .|..:...||...  ...:......|.....:..|.:|.||.
Human    67 ASAAAL---TAHLGSVHPH----ASFQAAARSPLRP--TPVVAPSEVPAGFPQRLSPLSAAYHHH 122

  Fly   151 QPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAA 215
            .|...............|..:.|...|.|.|.       ......|::.:|.|.::::.......
Human   123 HPQQQQQQQQPQQQQPPPPPRAGALQPPASGT-------RVVPNPHHSGSAPAPSSKDLKFGIDR 180

  Fly   216 AAAAAAAAGV--------AAPPVDGGVDGGV---GLAPPAG---GDLDDSSDYHEENEDCDSGNM 266
            ..:|.....|        ....:.||...||   ||.|.||   ..||.               :
Human   181 ILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDP---------------I 230

  Fly   267 DDHSVCSNGGKDDDGNSVKSGSTSDMSG-------------LSKKQRKARTAFTDHQLQTLEKSF 318
            ::.|...:....:..|||:........|             ..:|:..:|..|::.|.:.|||.|
Human   231 NEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRF 295

  Fly   319 ERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWK--RQTAVGLELLAEAGNFAAFQRLYGGS 381
            |.|||::..:|::||..|.|:|.|||.|:||||.||:  ::.....:...|||     ::..||:
Human   296 EIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAG-----EKPSGGA 355

  Fly   382 PYLGAWPYAAAAGAAHGATP-------------HTNIDIYYRQAAAAAAMQKPLPYNLYAGVP-- 431
            |        ||.|.....:|             ..::|:...........::.|........|
Human   356 P--------AADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVT 412

  Fly   432 -------SVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGG 489
                   |.|.|...|.|...||.    ||.|||||...||..|:               |:|||
Human   413 GALITASSAGSGGSSGGGGNSFSF----SSASSLSSSSTSAGCAS---------------SLGGG 458

  Fly   490 SPPSGLVKPIPAHSASASPPPRPP 513
                |..:.:||...:||..|:.|
Human   459 ----GASELLPATQPTASSAPKSP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeobox	303..355	CDD:278475	26/51 (51%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173		12/61 (20%)
		Abdominal-A	227..>344	CDD:332641	35/131 (27%)
		Homeobox	279..332	CDD:306543	26/52 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		42/184 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810