DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment B-H1 and dbx1b

DIOPT Version :9

Sequence 1:	NP_523387.1	Gene:	B-H1 / 32724	FlyBaseID:	FBgn0011758	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_571253.1	Gene:	dbx1b / 30416	ZFINID:	ZDB-GENE-000128-11	Length:	322	Species:	Danio rerio

Alignment Length:	274	Identity:	68/274 - (24%)
Similarity:	99/274 - (36%)	Gaps:	74/274 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 VLPSALHHPQPHP-------------------PTHPH---------THPHALMH-----PHGKLG 173
            :|||.:..|..:|                   .||..         :.|.|.||     |...
Zfish     2 MLPSVIAPPAMYPSFLRPSSALSLPPALQSAFTTHSSFLVEDLLRISRPAAFMHRSIPSPSAS-- 64

  Fly   174 HFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAA-----------AAAAAAAGVAA 227
              ||..|...||....|.     :.|.:.|.|.|:::...:.:           |..|:....|:
Zfish    65 --PPATGVTTLNTTSSAV-----HVAMSTALAKRSSSPQTSISSDPNYLKFGVNAILASTTRNAS 122

  Fly   228 PPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDM 292
            ||            ||..|....:..:     .|..|:.......|..........:.......:
Zfish   123 PP------------PPVQGMNAKTFPF-----PCFDGSFHPFIRASYFPASSSAVPIPGTFAWPL 170

  Fly   293 SGLSKKQR--KARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWK 355
            :...|.:|  ..|..|:|.|.:.|||.|::|||:|..:|::||.||.|.|.|||.|:||||.||:
Zfish   171 TARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLATKLGLKDSQVKIWFQNRRMKWR 235

  Fly   356 RQTAVGLELLAEAG 369
            ....  .|||:..|
Zfish   236 NSKE--RELLSSGG 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeobox	303..355	CDD:278475	28/51 (55%)
dbx1b	NP_571253.1	COG5576	<173..296	CDD:227863	35/77 (45%)
		Homeobox	182..235	CDD:278475	28/52 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	238..266		4/12 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	296..322
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810