Protein Alignment B-H1 and hoxd3a

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_571200.1
• Gene: hoxd3a / 30349
• ZFINID: ZDB-GENE-990415-120
• Length: 396
• Species: Danio rerio
• Alignment Length: 436
• Identity: 99/436 - (22%)
• Similarity: 152/436 - (34%)
• Gaps: 128/436 - (29%)

  Fly   108 NNSGSSGGSS----------PAHSN-NNNNINGDNCEASNVAGVGVLPSALHHPQPHPP-----T 156
            :|:|..||.|          |.|.. ::::|..|                  :..|..|     .
Zfish     8 DNAGLFGGYSYPKSDSYTYGPTHQGFSSSSIEND------------------YQSPICPIQTTSV 54

  Fly   157 HPHTHPH-----ALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAA 216
            ...||.:     :.|.|....|:..|.           :.:.||..|..||::.:.:..:.....
Zfish    55 RQATHKNGDINGSCMRPSASQGNSQPE-----------SISEQQQAAPLAASSPSPSTNSTQKKK 108

  Fly   217 AAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDG 281
            :.::..:..|.|.:...:                 ..:.:|..              ...|....
Zfish   109 SPSSNGSSTATPVISKQI-----------------FPWMKETR--------------QNAKQKST 142

  Fly   282 NSVKSGST-SDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKT 345
            |...:|.| .|.|......::.|||:|..||..|||.|...:||....|.|:|:.|:|::.|:|.
Zfish   143 NCPAAGETCDDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 207

  Fly   346 WYQNRRTKWKR-QTAVGLELLAEAGNFAAFQRLYGGSPYLG---------AWPYAAAAGAAHGAT 400
            |:||||.|:|: |.:.|: :.:..|:.........||.::|         :..|.|.:..:. |.
Zfish   208 WFQNRRMKYKKDQKSKGI-MHSPLGHSPDRSPPLSGSNHIGYSGQLPNVNSLSYDAPSPPSF-AK 270

  Fly   401 PHTNIDIYYRQAAAAAAM------QKPLPYNLY-------------AGVPSVGVGVG---VGVGP 443
            |..||   |..||..|.:      ||..|...|             |.:.|..|.||   |...|
Zfish   271 PQQNI---YGLAAYTAPLGGCIPQQKRYPGTEYDHHSMQGNGSFANANLQSSPVYVGGNFVDSMP 332

  Fly   444 A--PFSHLSASSSLSSLSSYYQSAAAAASAANPGGPH--PVAPPPS 485
            |  |..:|......||.|..|..||..     ||..|  |..|.|:
Zfish   333 ASGPMFNLGHLPHPSSASVDYSCAAQI-----PGNHHHGPCDPHPT 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	25/55 (45%)
hoxd3a	NP_571200.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..163		26/204 (13%)
		COG5576	116..237	CDD:227863	38/152 (25%)
		Antp-type hexapeptide	126..131		0/21 (0%)
		Homeodomain	162..218	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..246		5/27 (19%)
		DUF4074	333..394	CDD:463833	15/46 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..396		4/10 (40%)