Protein Alignment B-H1 and TLX3

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_066305.2
• Gene: TLX3 / 30012
• HGNCID: 13532
• Length: 291
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 73/249 - (29%)
• Similarity: 95/249 - (38%)
• Gaps: 59/249 - (23%)

  Fly   144 PSALHHPQPHPP----------THPHTHPHALMHPHGK--LGHFPPTAGGNGLNVAQYAAAMQQH 196
            |::...|.||.|          :.......|...|.|.  ||. ||  ||.       ..|....
Human     4 PASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGG-PP--GGR-------PGATYPS 58

  Fly   197 YAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDC 261
            ..|:.|...|....|.:.:...:.|.|||...|....:.|.|  .||....|......
Human    59 LPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAV--PPPLPSALPAMPSV------- 114

  Fly   262 DSGNMDDHSVCSNGG-----KDDDGNSVKSGSTSD----------------MSGLSKKQRKARTA 305
                   .:|.|.||     .:.....||...|:.                .:....|::|.||:
Human   115 -------PTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTS 172

  Fly   306 FTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTA 359
            |:..|:..|||.|.|||||:..||..||..|.::|.|||||:|||||||:||||
Human   173 FSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTA 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	32/55 (58%)
TLX3	NP_066305.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		15/61 (25%)
		Homeodomain	167..223	CDD:459649	32/55 (58%)