Protein Alignment B-H1 and VENTX

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_055283.1
• Gene: VENTX / 27287
• HGNCID: 13639
• Length: 258
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 79/293 - (26%)
• Similarity: 114/293 - (38%)
• Gaps: 88/293 - (30%)

  Fly   241 APPAG-------GDLD-------DSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSD 291
            :||.|       |.:|       ....:.....|...|::......|...:.....|:|..:.|.
Human     6 SPPRGPQQLSSFGSVDWLSQSSCSGPTHTPRPADFSLGSLPGPGQTSGAREPPQAVSIKEAAGSS 70

  Fly   292 --------MSGLSKKQR-----KARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQV 343
                    |:||||:..     :.|||||..|::|||..|:..:|||..||:.||.::.||:.|:
Human    71 NLPAPERTMAGLSKEPNTLRAPRVRTAFTMEQVRTLEGVFQHHQYLSPLERKRLAREMQLSEVQI 135

  Fly   344 KTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLG---AWP--YAAAAGAAHGATPHT 403
            |||:||||.|.|||                .|.....||:.|   |.|  |:.::|.|:|
Human   136 KTWFQNRRMKHKRQ----------------MQDPQLHSPFSGSLHAPPAFYSTSSGLANG----- 179

  Fly   404 NIDIYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAA 468
                          :|...|:...:|               |.:.:....|...|....|.|.|:
Human   180 --------------LQLLCPWAPLSG---------------PQALMLPPGSFWGLCQVAQEALAS 215

  Fly   469 ASAANPGGP---HPVAP-PPSVGG--GSPPSGL 495
            |.|:..|.|   ||..| .||:|.  .:.|.||
Human   216 AGASCCGQPLASHPPTPGRPSLGPALSTGPRGL 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	28/60 (47%)
VENTX	NP_055283.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		16/86 (19%)
		Homeodomain	93..148	CDD:459649	28/54 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..248		7/20 (35%)