Protein Alignment B-H1 and GBX1

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001092304.1
• Gene: GBX1 / 2636
• HGNCID: 4185
• Length: 363
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 96/341 - (28%)
• Similarity: 127/341 - (37%)
• Gaps: 97/341 - (28%)

  Fly   112 SSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQP---------HP---PTHPHTHPHA 164
            :.|||:|. .|......|.....|       :.|.:..|.|         :|   |..|...|.|
Human     4 AGGGSAPG-GNGGGGGGGPGTAFS-------IDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQA 60

  Fly   165 LMH---PHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAA----------AAAAA 216
            |..   |.| |....|.|...|.....:.|.:.|...:..|...|..:.|          ..|||
Human    61 LAPAPLPAG-LPPLAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYGPQELAAA 124

  Fly   217 AAAAAAAGVAAPPVDGG--VDGGV---GLAP-----------------------PAGGDLDDSSD 253
            ||||||......|..||  .:||:   .|.|                       ||.|.:..|.:
Human   125 AAAAAATAARNNPEPGGRRPEGGLEADELLPAREKVAEPPPPPPPHFSETFPSLPAEGKVYSSDE 189

  Fly   254 YHEENEDCDSGNMDDHSVCSNGGKDDDG--------------------NSVKSGS------TSDM 292
            ...|....|....:.....|.|..:|||                    .|:.:|:      |:.:
Human   190 EKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKLKGSLGTGAEEGAPVTAGV 254

  Fly   293 SGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQ 357
            :....|.|:.|||||..||..|||.|..:||||:.||.::||.|.||:.|||.|:||||.||||
Human   255 TAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR- 318

  Fly   358 TAVGLELLAEAGNFAA 373
                    .:|||.::
Human   319 --------IKAGNVSS 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	33/55 (60%)
GBX1	NP_001092304.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		8/34 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..265		26/136 (19%)
		Homeodomain	262..318	CDD:459649	33/55 (60%)