Protein Alignment B-H1 and NKX2-8

DIOPT Version :10

• Sequence 1: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 65/220 - (29%)
• Similarity: 93/220 - (42%)
• Gaps: 51/220 - (23%)

  Fly   260 DCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYL 324
            |.:.|:.......|......|.:...|...:.....::|::|.|..|:..|...||:.|.:|:||
Human    45 DSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYL 109

  Fly   325 SVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLY----------- 378
            |..||::||..|.|:..|||.|:||.|.|.||..|.|   .||:.:.||...|:
Human   110 SAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPG---AAESPDLAASAELHAAPGLLRRVVV 171

  Fly   379 ------------GGSPYLGAWPYAAAAGAAHGATPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVP 431
                        ||...:|    .|||....||.|            |||.   |||     |.|
Human   172 PVLVRDGQPCGGGGGGEVG----TAAAQEKCGAPP------------AAAC---PLP-----GYP 212

  Fly   432 SVGVGVGVGVGPAPFSHLSASSSLS 456
            :.|.|..:|:.|| :.||::.:.:|
Human   213 AFGPGSALGLFPA-YQHLASPALVS 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	25/55 (45%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		6/41 (15%)
		Homeodomain	85..141	CDD:459649	25/55 (45%)